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Literature summary extracted from

  • Misono, H.; Kawabata, Y.; Toyosato, M.; Yamamoto, T.; Soda, K.
    Purification and properties of L-methionine decarboxylase of Streptomyces sp. (1980), Bull. Inst. Chem. Res. Kyoto Univ., 58, 323-333.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.57 Ag2SO4
-
 Streptomyces sp.
4.1.1.57 CuSO4
-
 Streptomyces sp.
4.1.1.57 cycloserine
-
 Streptomyces sp.
4.1.1.57 cysteine
-
 Streptomyces sp.
4.1.1.57 D-Met
-
 Streptomyces sp.
4.1.1.57 FeSO4
-
 Streptomyces sp.
4.1.1.57 HgCl2
-
 Streptomyces sp.
4.1.1.57 Penicillamine
-
 Streptomyces sp.
4.1.1.57 phenylhydrazine
-
 Streptomyces sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.57 5
-
 L-Met
-
 Streptomyces sp.
4.1.1.57 16
-
 L-norleucine
-
 Streptomyces sp.
4.1.1.57 44
-
 S-ethyl-L-Cys
-
 Streptomyces sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.57 130000
-
 gel filtration Streptomyces sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.57 L-Met Streptomyces sp. induced by L-Met ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.57 Streptomyces sp.
-
 strain 590, strain 591, strain 592
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.57
-
 Streptomyces sp.

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.57 29.7
-
-
 Streptomyces sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.57 DL-Homocysteine 24% of the activity with L-Met Streptomyces sp. 3-Thiopropanamine + CO2
-
 ?
4.1.1.57 L-Ethionine 7.8% of the activity with L-Met Streptomyces sp. 3-Ethylthiopropanamine + CO2
-
 ?
4.1.1.57 L-Ethionine 19% of the activity with L-Met Streptomyces sp. 3-Ethylthiopropanamine + CO2
-
 ?
4.1.1.57 L-Ile 24.2% of the activity with L-Met Streptomyces sp. 2-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Ile 29% of the activity with L-Met Streptomyces sp. 2-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Leu 15% of the activity with L-Met Streptomyces sp. 3-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Leu 5.3% of the activity with L-Met Streptomyces sp. 3-Methylbutylamine + CO2
-
 ?
4.1.1.57 L-Met
-
 Streptomyces sp. 3-Methylthiopropanamine + CO2
-
 ?
4.1.1.57 L-Met induced by L-Met Streptomyces sp. ?
-
 ?
4.1.1.57 L-norleucine 45.3% of the activity with L-Met Streptomyces sp. pentanamine + CO2
-
 ?
4.1.1.57 L-norleucine 63% of the activity with L-Met Streptomyces sp. pentanamine + CO2
-
 ?
4.1.1.57 L-Norvaline 22% of the activity with L-Met Streptomyces sp. Butylamine + CO2
-
 ?
4.1.1.57 L-Norvaline 34% of the activity with L-Met Streptomyces sp. Butylamine + CO2
-
 ?
4.1.1.57 S-Ethyl-L-Cys 29.3% of the activity with L-Met Streptomyces sp. 2-Ethylthioethanamine + CO2
-
 ?
4.1.1.57 S-Ethyl-L-Cys 61% of the activity with L-Met Streptomyces sp. 2-Ethylthioethanamine + CO2
-
 ?
4.1.1.57 S-Methyl-L-Cys 13% of the activity with L-Met Streptomyces sp. 2-Methylthioethanamine + CO2
-
 ?
4.1.1.57 S-Methyl-L-Met 13% of the activity with L-Met Streptomyces sp. 3-Dimethylthiopropanamine + CO2
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
4.1.1.57 45
-
 pH 7.2, stable up to Streptomyces sp.
4.1.1.57 50
-
 pH 5.5, stable up to Streptomyces sp.

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.57 6.4
-
-
 Streptomyces sp.

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.57 4.2 8.5 pH 4.2: about 35% of maximal activity, pH 8.5: about 45% of maximal activity Streptomyces sp.

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
4.1.1.57 4.5 6 stable in the range Streptomyces sp.

Cofactor

EC Number Cofactor Comment Organism Structure
4.1.1.57 pyridoxal 5'-phosphate stimulates Streptomyces sp.