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Literature summary extracted from

  • Snell, E.E.; Smucker, A.A.; Ringelmann, E.; Lynen, F.
    Die bakterielle Oxydation des Vitamin B6. Die enzymatische Decarboxylierung von 2-Methyl-3-hydroxy-pyridin-4,5-dicarbonsaeure (1964), Biochem. Z., 341, 109-119.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.51 Reducing agent e.g. cyanide or SH-reagents, required Pseudomonas sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.51 0.036
-
 3-hydroxy-2-methylpyridine-4,5-dicarboxylate
-
 Pseudomonas sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.51 Mn2+ required Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.51 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Pseudomonas sp. inducible enzyme. Essential reaction in the degradative utilization of vitamin B6 as an energy and carbon source ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.51 Pseudomonas sp.
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.51
-
 Pseudomonas sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.51 culture condition:pyridoxine-grown cell as principal source of carbon and nitrogen Pseudomonas sp.
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.51 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate
-
 Pseudomonas sp. 3-Hydroxy-2-methylpyridine-5-carboxylate + CO2
-
 ?
4.1.1.51 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate inducible enzyme. Essential reaction in the degradative utilization of vitamin B6 as an energy and carbon source Pseudomonas sp. ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.51 7.8
-
-
 Pseudomonas sp.

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.51 6.5 8.9 pH 6.5: about 40% of maximal activity, pH 8.9: about 60% of maximal activity Pseudomonas sp.