Literature summary extracted from

Regenass, U.; Mett, H.; Stanek, J.; Mueller, M.; Kramer, D.; Porter, C.W.
CGP 48664, a new S-adenosylmethionine decarboxylase inhibitor with broad spectrum antiproliferative and antitumor activity (1994), Cancer Res., 54, 3210-3217.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
4.1.1.50	4-Amidinoindan-1-(2'-amidino)hydrazone	i.e. CGP 48664	Mus musculus
4.1.1.50	methylglyoxal bis(guanylhydrazone)	-	Homo sapiens
4.1.1.50	methylglyoxal bis(guanylhydrazone)	-	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
4.1.1.50	Homo sapiens	-	-	-
4.1.1.50	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
4.1.1.50	melanoma cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4.1.1.50	S-adenosyl-L-methionine	-	Mus musculus	(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2	-	?
4.1.1.50	S-adenosyl-L-methionine	-	Homo sapiens	(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2	-	?

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Release 2023.1 (January 2023)