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Literature summary extracted from

  • Pösö, H.; Pegg, A.E.
    Comparison of S-adenosylmethionine decarboxylase from rat liver and muscle (1982), Biochemistry, 21, 3116-3122.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.50 1,3-diaminopropane enzyme from psoas is stimulated more than enzyme from liver Rattus norvegicus
4.1.1.50 putrescine stimulation Rattus norvegicus
4.1.1.50 putrescine 0.25 mM required for maximal activation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.50 Dimethylglyoxal bis(guanylhydrazone)
-
 Rattus norvegicus
4.1.1.50 ethylglyoxal bis(guanylhydrazone)
-
 Rattus norvegicus
4.1.1.50 methylglyoxal bis(guanylhydrazone)
-
 Rattus norvegicus
4.1.1.50 n-Butylglyoxal bis(guanylhydrazone)
-
 Rattus norvegicus
4.1.1.50 Pentane dialdehyde bis(guanylhydrazone) weak Rattus norvegicus
4.1.1.50 Propane dialdehyde bis(guanylhydrazone) weak Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.50 0.05
-
 S-adenosyl-L-methionine enzyme from liver Rattus norvegicus
4.1.1.50 0.1
-
 S-adenosyl-L-methionine enzyme from psoas Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.50 32500
-
 2 * 32500, SDS-PAGE Rattus norvegicus
4.1.1.50 68000
-
 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.50 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.50
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.50 liver
-
 Rattus norvegicus
-
4.1.1.50 muscle
-
 Rattus norvegicus
-
4.1.1.50 psoas
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.50 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.50 S-adenosyl-L-methionine
-
 Rattus norvegicus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.50 dimer 2 * 32500, SDS-PAGE Rattus norvegicus