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Literature summary extracted from
- S-Adenosylmethionine decarboxylase (Escherichia coli) (1983), Methods Enzymol., 94, 228-230.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.50 | pyruvate | each subunit contains one covalently linked pyruvate | Escherichia coli |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.50 | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt | competitive with respect to S-adenosylmethionine | Escherichia coli | |
| 4.1.1.50 | methylglyoxal bis(guanylhydrazone) | - |
Escherichia coli | |
| 4.1.1.50 | NaCNBH3 | inactivation in presence of adenosylmethionine and Mg2+, no inactivation in absence of substrate and Mg2+ | Escherichia coli | |
| 4.1.1.50 | phenylhydrazine | - |
Escherichia coli | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.50 | Ca2+ | requires a divalent cation, Mg2+, Ca2+ or Mn2+ | Escherichia coli | |
| 4.1.1.50 | Mg2+ | requires a divalent cation, Mg2+, Ca2+ or Mn2+ | Escherichia coli | |
| 4.1.1.50 | Mn2+ | requires a divalent cation, Mg2+, Ca2+ or Mn2+ | Escherichia coli | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.50 | 17000 | - |
6 * 17000 | Escherichia coli |
| 4.1.1.50 | 108000 | - |
- |
Escherichia coli |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.50 | Escherichia coli | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.50 | - |
Escherichia coli |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.50 | 0.88 | - |
- |
Escherichia coli |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.50 | S-adenosyl-L-methionine | - |
Escherichia coli | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 4.1.1.50 | hexamer | 6 * 17000 | Escherichia coli |
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Release 2023.1 (January 2023)
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