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Literature summary extracted from

  • Hoffmann, A.; Hilpert, W.; Dimroth, P.
    The carboxyltransferase activity of the sodium-ion-translocating methylmalonyl-CoA decarboxylase of Veillonella alcalescens (1989), Eur. J. Biochem., 179, 645-650.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.1.3.1 membrane
-
 Veillonella parvula 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.1 Veillonella parvula
-
 activity is located on the alpha-subunit of membrane-bound methylmalonyl-CoA decarboxylase EC 4.1.1.41
-
7.2.4.3 Veillonella parvula
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.3.1 affinity chromatography on avidin-Sepharose Veillonella parvula

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.1 acetyl-CoA + oxaloacetate
-
 Veillonella parvula malonyl-CoA + pyruvate
-
 ?
2.1.3.1 propionyl-CoA + oxaloacetate
-
 Veillonella parvula (S)-methylmalonyl-CoA + pyruvate
-
 r
7.2.4.3 (S)-methylmalonyl-CoA + Na+[side 1] + H+[side 2]
-
 Veillonella parvula propanoyl-CoA + CO2 + Na+[side 2]
-
 ?
7.2.4.3 additional information Na+-independent carboxyltransferase activity: catalyzes the isotopic exchange between methylmalonyl-CoA and [1-14C]propionyl-CoA or between malonyl-CoA and [1-14C]acetyl-CoA, catalyzes the carboxyl transfer reaction from methylmalonyl-CoA to acetyl-CoA yielding propionyl-CoA and malonyl-CoA and vice versa Veillonella parvula ?
-
 ?

Subunits

EC Number Subunits Comment Organism
7.2.4.3 ? the following functions are assigned to the different polypeptide chains: alpha /carboxyltransferase, beta /carboxybiotin-carrier-protein decarboxylase, gamma /biotin carrier protein Veillonella parvula