Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Airas, R.K.
    Analysis of the isoleucyl-tRNA synthetase reaction by total rate equation. Magnesium and spermidine in the tRNA kinetics (1992), Eur. J. Biochem., 210, 451-454.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
6.1.1.5 spermidine at least 2 bound Mg2+ or spermidines required for binding of tRNA to the enzyme Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.1.1.5 diphosphate partly inhibits the binding of tRNA Escherichia coli
6.1.1.5 tRNA partly inhibits the binding of diphosphate Escherichia coli

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.1.1.5 Mg2+ at least 2 bound Mg2+ or spermidines required for the binding of tRNA to the enzyme Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
6.1.1.5 Escherichia coli
-
 B
-
6.1.1.5 Escherichia coli B / ATCC 11303
-
 B
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
 Escherichia coli AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
6.1.1.5 ATP + L-isoleucine + tRNAIle
-
 Escherichia coli B / ATCC 11303 AMP + diphosphate + L-isoleucyl-tRNAIle
-
 ?
6.1.1.5 additional information Ile + ATP + enzyme/Ile-AMP-enzyme + diphosphate, isoleucine-dependent ATP-diphosphate exchange Escherichia coli ?
-
 ?
6.1.1.5 additional information Ile + ATP + enzyme/Ile-AMP-enzyme + diphosphate, isoleucine-dependent ATP-diphosphate exchange Escherichia coli B / ATCC 11303 ?
-
 ?