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Literature summary extracted from

  • Felix, F.; Brouillet, N.
    Purification and properties of uroporphyrinogen decarboxylase from Saccharomyces cerevisiae (1990), Eur. J. Biochem., 188, 393-403.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.37 5,5'-dithiobis(2-nitrobenzoate)
-
 Saccharomyces cerevisiae
4.1.1.37 Cu2+
-
 Saccharomyces cerevisiae
4.1.1.37 Fe2+
-
 Saccharomyces cerevisiae
4.1.1.37 Fe3+
-
 Saccharomyces cerevisiae
4.1.1.37 PCMB
-
 Saccharomyces cerevisiae
4.1.1.37 Zn2+
-
 Saccharomyces cerevisiae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.37 0.000006
-
 uroporphyrinogen III
-
 Saccharomyces cerevisiae
4.1.1.37 0.000007
-
 7-COOH-porphyrinogen I
-
 Saccharomyces cerevisiae
4.1.1.37 0.00001
-
 Uroporphyrinogen I
-
 Saccharomyces cerevisiae

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
4.1.1.37 38000
-
 1 * 38000, SDS-PAGE Saccharomyces cerevisiae
4.1.1.37 46000
-
 gel filtration Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.37 Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.1.37
-
 Saccharomyces cerevisiae

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
4.1.1.37 0.029
-
-
 Saccharomyces cerevisiae

Storage Stability

EC Number Storage Stability Organism
4.1.1.37 -20°C, stable for several months Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.37 7-COOH-porphyrinogen I
-
 Saccharomyces cerevisiae Coproporphyrinogen I + CO2
-
 ?
4.1.1.37 uroporphyrinogen I
-
 Saccharomyces cerevisiae coproporphyrinogen I + 4 CO2
-
 ?
4.1.1.37 Uroporphyrinogen III
-
 Saccharomyces cerevisiae Coproporphyrinogen III + 4 CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
4.1.1.37 monomer 1 * 38000, SDS-PAGE Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.37 5.7
-
 uroporphyrinogen I, uroporphyrinogen III or 7-COOH-porphyrinogen I, estimation by coproporphyrinogen formation Saccharomyces cerevisiae