EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
4.1.1.37 | 5,5'-dithiobis(2-nitrobenzoate) | - |
Rattus norvegicus | |
4.1.1.37 | Fe2+ | 0.45 mM Fe(NH4)2, 50% inhibition under anaerobic conditions in the dark. Competitive with uroporphyrinogen I and uroporphyrinogen II as substrates. Preincubation with 5-COOH-porphyrinogen protects | Rattus norvegicus | |
4.1.1.37 | Hg2+ | - |
Rattus norvegicus | |
4.1.1.37 | Zn2+ | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
4.1.1.37 | 0.0003 | - |
6-COOH-porphyrinogen I | - |
Rattus norvegicus | |
4.1.1.37 | 0.00133 | - |
5-COOH-porphyrinogen I | - |
Rattus norvegicus | |
4.1.1.37 | 0.00182 | - |
uroporphyrinogen III | - |
Rattus norvegicus | |
4.1.1.37 | 0.00285 | - |
6-COOH-porphyrinogen I | - |
Rattus norvegicus | |
4.1.1.37 | 0.00318 | - |
Uroporphyrinogen I | - |
Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
4.1.1.37 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
4.1.1.37 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
4.1.1.37 | 5-COOH-porphyrinogen I | - |
Rattus norvegicus | Coproporphyrinogen I + CO2 | - |
? | |
4.1.1.37 | 6-COOH-porphyrinogen I | - |
Rattus norvegicus | Coproporphyrinogen I + CO2 | - |
? | |
4.1.1.37 | 7-COOH-porphyrinogen I | - |
Rattus norvegicus | Coproporphyrinogen I + CO2 | - |
? | |
4.1.1.37 | uroporphyrinogen I | - |
Rattus norvegicus | coproporphyrinogen I + 4 CO2 | - |
? | |
4.1.1.37 | Uroporphyrinogen III | - |
Rattus norvegicus | Coproporphyrinogen III + 4 CO2 | - |
? |