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Literature summary extracted from

  • Miyazaki, S.S.; Toki, S.; Izumi, Y.; Yamada, H.
    Futher characterization of serine hydroxymethyltransferase from a serine-producing methylotroph, Hyphomicrobium methylovorum (1987), Agric. Biol. Chem., 51, 2587-2589.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.2.1 beta-chloroalanine suicide substrate Hyphomicrobium methylovorum
2.1.2.1 D-cycloserine
-
 Hyphomicrobium methylovorum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.2.1 L-serine + tetrahydrofolate Hyphomicrobium methylovorum key enzyme of serine pathway for assimilation of C1-compounds glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.2.1 Hyphomicrobium methylovorum
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.2.1 L-serine + tetrahydrofolate
-
 Hyphomicrobium methylovorum glycine + 5,10-methylenetetrahydrofolate + H2O
-
 r
2.1.2.1 L-serine + tetrahydrofolate key enzyme of serine pathway for assimilation of C1-compounds Hyphomicrobium methylovorum glycine + 5,10-methylenetetrahydrofolate + H2O
-
 ?
2.1.2.1 additional information no: D-serine Hyphomicrobium methylovorum ?
-
 ?
2.1.2.1 additional information no: D-threonine Hyphomicrobium methylovorum ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.2.1 tetrahydrofolate requirement with L-serine or L-2-methylserine as substrate Hyphomicrobium methylovorum