EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.1.2.1 | L-serine | - |
Mus musculus | |
2.1.2.1 | tetrahydrofolate derivatives | - |
Mus musculus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.2.1 | additional information | - |
additional information | - |
Mus musculus | |
2.1.2.1 | 0.15 | 0.9 | L-serine | - |
Mus musculus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.1.2.1 | cytoplasm | - |
Mus musculus | 5737 | - |
2.1.2.1 | mitochondrion | - |
Mus musculus | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.1.2.1 | 56000 | - |
4 * 56000, SDS-PAGE | Mus musculus |
2.1.2.1 | 215000 | - |
HPLC gel filtration | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.1 | L-serine + tetrahydrofolate | Mus musculus | main glycine source for purine biosynthetic pathway in ureide biogenesis | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? | |
2.1.2.1 | L-serine + tetrahydrofolate | Mus musculus | key enzyme of serine pathway for assimilation of C1-compounds | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.1.2.1 | Mus musculus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.1.2.1 | - |
Mus musculus |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.1.2.1 | 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine | mechanism | Mus musculus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.1.2.1 | L-1210 cell | transformed cells | Mus musculus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.1.2.1 | 9.7 | - |
- |
Mus musculus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.1.2.1 | L-serine + tetrahydrofolate | - |
Mus musculus | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? | |
2.1.2.1 | L-serine + tetrahydrofolate | main glycine source for purine biosynthetic pathway in ureide biogenesis | Mus musculus | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? | |
2.1.2.1 | L-serine + tetrahydrofolate | key enzyme of serine pathway for assimilation of C1-compounds | Mus musculus | glycine + 5,10-methylenetetrahydrofolate + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.1.2.1 | homotetramer | 4 * 56000, SDS-PAGE | Mus musculus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.2.1 | additional information | - |
additional information | - |
Mus musculus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.1.2.1 | additional information | - |
additional information | - |
Mus musculus |