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Literature summary extracted from
- Chemical modification of L-lactate 2-monooxygenase with fluorodinitrobenzene: evidence for two essential histidine residues (1983), Biochemistry, 22, 1665-1669.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.12.4 | fluorodintrobenzene | complete inactivation, incorporation of 1 mol dinitrophenyl per catalytic site | Mycolicibacterium smegmatis |  |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.12.4 | (S)-lactate + O2 | Mycolicibacterium smegmatis | - |
acetate + CO2 + H2O | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.13.12.4 | Mycolicibacterium smegmatis | - |
- |
- |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 1.13.12.4 | 53.6 | - |
- |
Mycolicibacterium smegmatis |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.13.12.4 | (S)-lactate + O2 | - |
Mycolicibacterium smegmatis | acetate + CO2 + H2O | - |
? | |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.13.12.4 | FMN | - |
Mycolicibacterium smegmatis | |
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Release 2023.1 (January 2023)
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