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Literature summary extracted from

  • Maruyama, K.; Yamauchi, T.; Yamamoto, S.; Hayaishi, O.
    A dehydrogenase reaction catalyzed by lysine monooxygenase, a flavooxygenase (1976), Arch. Biochem. Biophys., 173, 480-489.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.12.2 p-chloromercuribenzoate increases oxidase and dehydrogenase activities, maximal rate of oxidation of lysine at 4-5 mol p-chloromercuribenzoate per mol enzyme, for arginine at 3 mol per mol enzyme Pseudomonas fluorescens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.12.2 p-chloromercuribenzoate increases oxidase and dehydrogenase activities, decreases oxygenase activity Pseudomonas fluorescens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.12.2 0.018
-
 phenazine methosulfate dehydrogenation of alanine and propylamine Pseudomonas fluorescens
1.13.12.2 0.025
-
 arginine dehydrogenation with phenazine methosulfate Pseudomonas fluorescens
1.13.12.2 0.091
-
 L-lysine dehydrogenation with phenazine methosulfate Pseudomonas fluorescens
1.13.12.2 0.095
-
 arginine oxidation with O2 Pseudomonas fluorescens
1.13.12.2 0.125
-
 alanine + propylamine, oxidation with O2 Pseudomonas fluorescens
1.13.12.2 0.25
-
 ornithine oxidation with O2 Pseudomonas fluorescens
1.13.12.2 0.33
-
 lysine oxidation with O2 Pseudomonas fluorescens
1.13.12.2 0.42
-
 ornithine dehydrogenation with phenazine methosulfate Pseudomonas fluorescens
1.13.12.2 0.59
-
 arginine monooxygenation Pseudomonas fluorescens
1.13.12.2 0.67
-
 lysine monooxygenation Pseudomonas fluorescens

Organism

EC Number Organism UniProt Comment Textmining
1.13.12.2 Pseudomonas fluorescens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.12.2 alanine + propylamine + O2 monooxygenase and oxidase activity Pseudomonas fluorescens ?
-
 ?
1.13.12.2 alanine + propylamine + phenazine methosulfate anaerobic conditions, ferricyanide as terminal electron acceptor, dehydrogenase activity Pseudomonas fluorescens pyruvate + NH3 + reduced phenazine methosulfate
-
 ?
1.13.12.2 L-arginine + O2 monooxygenase activity Pseudomonas fluorescens 4-guanidinobutyramide + CO2 + H2O
-
 ?
1.13.12.2 L-arginine + O2 oxidase activity Pseudomonas fluorescens 2-amino-5-guanidinovalerate + NH3 + H2O2
-
 ?
1.13.12.2 L-arginine + phenazine methosulfate anaerobic conditions, ferricyanide as terminal electron acceptor, dehydrogenase activity Pseudomonas fluorescens 2-keto-5-guanidinovalerate + NH3 + reduced phenazine methosulfate
-
 ?
1.13.12.2 L-lysine + O2 monooxygenase activity Pseudomonas fluorescens 5-aminopentanamide + CO2 + H2O
-
 ?
1.13.12.2 L-lysine + O2 oxidase activity Pseudomonas fluorescens 2-keto-6-amino-n-hexanoate + NH3 + H2O2
-
 ?
1.13.12.2 L-lysine + phenazine methosulfate anaerobic conditions, ferricyanide as terminal electron acceptor, dehydrogenase activity Pseudomonas fluorescens 2-keto-6-amino-n-hexanoate + NH3 + reduced phenazine methosulfate
-
 ?
1.13.12.2 L-ornithine + phenazine methosulfate anaerobic conditions, ferricyanide as terminal electron acceptor, dehydrogenase activity Pseudomonas fluorescens 2-keto-5-aminopentanoate + NH3 + reduced phenazine methosulfate
-
 ?
1.13.12.2 additional information monooxygenase, oxidase and dehydrogenase reaction catalyzed by a single enzyme molecule Pseudomonas fluorescens ?
-
 ?