Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Ohnishi, T.; Yamamoto, S.; Hayaishi, O.; Izumi, T.; Shiba, T.
    Studies on the reaction specificity of the flavoprotein lysine monooxygenase with modified substrates (1976), Arch. Biochem. Biophys., 176, 358-365.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.12.2 4-Methyllysine at low substrate concentrations Pseudomonas fluorescens
1.13.12.2 5-Methyllysine at low substrate concentrations Pseudomonas fluorescens
1.13.12.2 Nepsilon-Methyllysine at low substrate concentrations Pseudomonas fluorescens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.12.2 4-Methyllysine at higher substrate concentrations, competitive inhibitor Pseudomonas fluorescens
1.13.12.2 5-Methyllysine at higher substrate concentrations, competitive inhibitor Pseudomonas fluorescens
1.13.12.2 Nepsilon-Methyllysine at higher substrate concentrations, competitive inhibitor Pseudomonas fluorescens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.12.2 additional information
-
 additional information
-
 Pseudomonas fluorescens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.13.12.2 additional information metals play no role in lysine monooxygenase Pseudomonas fluorescens

Organism

EC Number Organism UniProt Comment Textmining
1.13.12.2 Pseudomonas fluorescens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.12.2 4-chlorolysine + O2 oxidase activity Pseudomonas fluorescens ?
-
 ?
1.13.12.2 4-methyllysine + O2 oxidase activity Pseudomonas fluorescens 2-keto-4-methyl-6-amino-n-hexanoate + NH3 + H2O2
-
 ?
1.13.12.2 5-hydroxylysine + O2 oxidase activity Pseudomonas fluorescens ?
-
 ?
1.13.12.2 5-methyllysine + O2 monooxygenase activity Pseudomonas fluorescens 4-methyl-5-aminopentanamide + CO2 + H2O
-
 ?
1.13.12.2 L-homoarginine + O2
-
 Pseudomonas fluorescens ?
-
 ?
1.13.12.2 L-lysine + O2 monooxygenase activity Pseudomonas fluorescens 5-aminopentanamide + CO2 + H2O
-
 ?
1.13.12.2 additional information analogs with a modified carboxyl or alpha-amino group are inactive as substrates Pseudomonas fluorescens ?
-
 ?
1.13.12.2 additional information L-lysine analogs with a chloro or hydroxyl group at either the delta or the gamma position are both oxygenated and oxidized Pseudomonas fluorescens ?
-
 ?
1.13.12.2 Nepsilon-methyllysine + O2 monooxygenase activity Pseudomonas fluorescens 5-methylaminopentanamide + CO2 + H2O
-
 ?
1.13.12.2 threo-4-hydroxy-L-lysine + O2 oxidase activity Pseudomonas fluorescens ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.13.12.2 34
-
 assay at Pseudomonas fluorescens

Cofactor

EC Number Cofactor Comment Organism Structure
1.13.12.2 FAD contains 2 mol of FAD per mol of enzyme Pseudomonas fluorescens