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Literature summary extracted from

  • Rieske, J.S.
    Composition, structure, and function of complex III of the respiratory chain (1976), Biochim. Biophys. Acta, 456, 195-247.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
7.1.1.8 Antimycin
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
7.1.1.8 mitochondrion
-
 Cyberlindnera jadinii 5739
-
7.1.1.8 mitochondrion
-
 Bos taurus 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
7.1.1.8 Iron-sulfur cluster
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
7.1.1.8 8000
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 11500
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 15000
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 25000
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 43000
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 47000
-
 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus
7.1.1.8 207500
-
 summation of protein components Bos taurus
7.1.1.8 250000
-
 sedimentation velocity Bos taurus
7.1.1.8 262000 288000 light-scattering measurement Bos taurus
7.1.1.8 268000
-
 cytochrome c1 content Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
7.1.1.8 ubiquinone-10 + ferricytochrome c Cyberlindnera jadinii
-
 ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c Rattus norvegicus
-
 ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c Bos taurus
-
 ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c Columba sp.
-
 ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
7.1.1.8 Bos taurus
-
-
-
7.1.1.8 Columba sp.
-
 pigeon
-
7.1.1.8 Cyberlindnera jadinii
-
 yeast
-
7.1.1.8 Rattus norvegicus
-
 rat
-

Purification (Commentary)

EC Number Purification (Comment) Organism
7.1.1.8
-
 Bos taurus

Renatured (Commentary)

EC Number Renatured (Comment) Organism
7.1.1.8 reconstitution Cyberlindnera jadinii
7.1.1.8 reconstitution Rattus norvegicus
7.1.1.8 reconstitution Bos taurus
7.1.1.8 reconstitution Columba sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
7.1.1.8 heart
-
 Rattus norvegicus
-
7.1.1.8 heart
-
 Columba sp.
-
7.1.1.8 heart heart muscle Bos taurus
-
7.1.1.8 liver
-
 Rattus norvegicus
-
7.1.1.8 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Cyberlindnera jadinii ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Rattus norvegicus ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Bos taurus ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinol + 2 ferricytochrome c
-
 Columba sp. ubiquinone + 2 ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c
-
 Cyberlindnera jadinii ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c
-
 Rattus norvegicus ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c
-
 Bos taurus ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?
7.1.1.8 ubiquinone-10 + ferricytochrome c
-
 Columba sp. ubiquinol-10 + ferrocytochrome c + 2 H+
-
 ?

Subunits

EC Number Subunits Comment Organism
7.1.1.8 oligomer 2 * 15000 + 1 * 43000 + 1 * 25000 + 1 * 11500 + 1 * 47000 + 1 * 43000 + 1 * 8000, multicomponent complex with 2 molecules of cytochrome b, one molecule each of cytochrome c1, iron-sulfur protein, antimycin-binding protein, core protein I, core protein II and one unknown peptide, SDS-PAGE Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
7.1.1.8 cytochrome b
-
 Bos taurus
7.1.1.8 cytochrome c1
-
 Bos taurus