Literature summary extracted from

Calderone, V.; Trabucco, M.; Menin, V.; Negro, A.; Zanotti, G.
Cloning of human 3-hydroxyanthranilic acid dioxygenase in Escherichia coli: characterisation of the purified enzyme and its in vitro inhibition by Zn2+ (2002), Biochim. Biophys. Acta, 1596, 283-292.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.13.11.6	expression in Escherichia coli	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.6	Cd2+	-	Homo sapiens
1.13.11.6	additional information	not: Mn2+, Ni2+, Cu2+, Re3+, Os3+, Pb2+	Homo sapiens
1.13.11.6	Zn2+	-	Homo sapiens

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
1.13.11.6	soluble	-	Homo sapiens	-	-

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.13.11.6	Fe2+	requirement	Homo sapiens

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.13.11.6	36000	-	SDS-PAGE	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.6	3-hydroxyanthranilate + O2	Homo sapiens	-	2-amino-3-carboxymuconate semialdehyde	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.6	Homo sapiens	-	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
1.13.11.6	3-hydroxyanthranilate + O2 = 2-amino-3-carboxymuconate semialdehyde	mechanism	Homo sapiens	a

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.6	3-hydroxyanthranilate + O2	-	Homo sapiens	2-amino-3-carboxymuconate semialdehyde	-	?
1.13.11.6	3-hydroxyanthranilate + O2	-	Homo sapiens	2-amino-3-carboxymuconate semialdehyde	-	r

Turnover Number [1/s]

EC Number	Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
1.13.11.6	additional information	-	additional information	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)