Literature summary extracted from

Fornstedt-Wallin, B.; Lundstrom, J.; Fredriksson, G.; Schwarcz, R.; Luthman, J.
3-Hydroxyanthranilic acid accumulation following administration of the 3-hydroxyanthranilic acid 3,4-dioxygenase inhibitor NCR-631 (1999), Eur. J. Pharmacol., 386, 15-24.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.13.11.6	4,6-dibromo-3-hydroxyanthranilic acid	NCR-631, characterization of in vivo effects, reversible inhibition with short half-life following systematic administration	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.6	Rattus norvegicus	-	Sprague Dawley	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.6	astrocyte	-	Rattus norvegicus	-
1.13.11.6	brain	-	Rattus norvegicus	-
1.13.11.6	plasma	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.6	3-hydroxyanthranilate + O2	-	Rattus norvegicus	2-amino-3-carboxymuconate semialdehyde	-	?

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Release 2023.1 (January 2023)