EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
1.14.12.12 | D362A | mutation in alpha subunit of terminal dioxygenase ISPNAP, no activity with naphthalene, biphenyl and phenanthrene | Pseudomonas sp. |
1.14.12.12 | F202L | mutation in alpha subunit of terminal dioxygenase ISPNAP, no activity with naphthalene, biphenyl and phenanthrene | Pseudomonas sp. |
1.14.12.12 | F202V | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | F352L | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type, major product of biphenyl oxidation: biphenyl-3,4-dihydrodiol instead of biphenyl-2,3-dihydrodiol | Pseudomonas sp. |
1.14.12.12 | F352V | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type, product of biphenyl oxidation: 96% biphenyl-3,4-dihydrodiol instead of biphenyl-2,3-dihydrodiol | Pseudomonas sp. |
1.14.12.12 | M366W | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | N201A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene as wild-type, very weak activity with biphenyl | Pseudomonas sp. |
1.14.12.12 | N201Q | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | N201S | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | T351N | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | T351R | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | T351S | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | V260A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | V260L | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | V260N | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | W316A | mutation in alpha subunit of terminal dioxygenase ISPNAP, similar activity with naphthalene, biphenyl and phenanthrene as wild-type | Pseudomonas sp. |
1.14.12.12 | W358A | mutation in alpha subunit of terminal dioxygenase ISPNAP, very low activity with naphthalene and biphenyl | Pseudomonas sp. |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.12.12 | Pseudomonas sp. | - |
strain NCIB 9816/11, naphthalene dihydrogenase mutant derived from strain NCIB 9816-4 oxidizing naphthalene to cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene | - |