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Literature summary extracted from
- Catabolism of L-ascorbate in animal tissues (1970), Methods Enzymol., 18, 46-50.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.34 | 8-hydroxyquinoline | Mn2+ or Mg2+ restore activity | Rattus norvegicus |  |
| 4.1.1.34 | diisopropylfluorophosphate | - |
Rattus norvegicus | |
| 4.1.1.34 | Metal chelating agents | - |
Rattus norvegicus | |
| 4.1.1.34 | monoiodoacetate | - |
Rattus norvegicus | |
| 4.1.1.34 | PCMB | - |
Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.34 | 2,3-Diketo-L-gulonic acid | Rattus norvegicus | enzyme is involved in the catabolism of L-ascorbate | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.34 | Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 4.1.1.34 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.34 | liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.34 | additional information | - |
- |
Rattus norvegicus |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 4.1.1.34 | -20°C, partially purified enzyme, stable for months | Rattus norvegicus |
| 4.1.1.34 | 0°C, purified enzyme, stable for 1 week | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.34 | 2,3-Diketo-D-glucoheptonic acid | - |
Rattus norvegicus | ? | - |
? | |
| 4.1.1.34 | 2,3-Diketo-D-gluconic acid | - |
Rattus norvegicus | ? | - |
? | |
| 4.1.1.34 | 2,3-Diketo-D-gulonic acid | - |
Rattus norvegicus | D-Xylulose + CO2 | - |
? | |
| 4.1.1.34 | 2,3-Diketo-D-pentonic acid | - |
Rattus norvegicus | ? | - |
? | |
| 4.1.1.34 | 2,3-Diketo-L-gluconic acid | - |
Rattus norvegicus | ? | - |
? | |
| 4.1.1.34 | 2,3-Diketo-L-gulonic acid | - |
Rattus norvegicus | D-Xylonic acid + CO2 | - |
? | |
| 4.1.1.34 | 2,3-Diketo-L-gulonic acid | enzyme is involved in the catabolism of L-ascorbate | Rattus norvegicus | ? | - |
? | |
| 4.1.1.34 | 2,3-Diketo-L-pentonic acid | - |
Rattus norvegicus | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.34 | 7 | - |
- |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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