Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Colombo, G.; Rajashekhar, B.; Giedroc, D.P.; Villafranca, J.J.
    Alternate substrates of dopamine beta-hydroxylase. I. Kinetic investigations of benzyl cyanides as substrates and inhibitors (1984), J. Biol. Chem., 259, 1593-1600.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.17.1 4-Hydroxybenzyl cyanide
-
 Bos taurus
1.14.17.1 additional information suicide inactivation by benzyl cyanides Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.17.1 additional information
-
 additional information Km of benzyl cyanide analogs with or without 6% dimethylformamide Bos taurus
1.14.17.1 0.14
-
 O2 in presence of tyramine Bos taurus
1.14.17.1 1.3
-
 tyramine
-
 Bos taurus
1.14.17.1 1.6
-
 4-Hydroxybenzyl cyanide
-
 Bos taurus
1.14.17.1 2.8
-
 O2 in the presence of p-hydroxybenzyl cyanide Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.14.17.1 Bos taurus
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.14.17.1 additional information
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.17.1 3,4-dihydroxyphenethylamine + ascorbate + O2
-
 Bos taurus noradrenaline + dehydroascorbate + H2O norepinephrine ?
1.14.17.1 4-hydroxybenzyl cyanide + ascorbate + O2 and benzyl cyanide analogs Bos taurus 4-hydroxymandelonitrile + dehydroascorbate + H2O
-
 ?
1.14.17.1 tyramine + ascorbate + O2
-
 Bos taurus octopamine + dehydroascorbate + H2O
-
 ?