Literature summary extracted from

DeWolf, W.E.; Carr, S.A.; Varrichio, A.; Goodhart, P.J.; Mentzer, M.A.; Roberts, G.D.; Southan, C.; Dolle, R.E.; Kruse, L.I.
Inactivation of dopamine beta-hydroxylase by p-cresol: isolation and characterization of covalently modified active site peptides (1988), Biochemistry, 27, 9093-9101.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.14.17.1	p-Cresol	mechanism of inhibition	Bos taurus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.14.17.1	3,4-dihydroxyphenethylamine + ascorbate + O2	Bos taurus	-	noradrenaline + dehydroascorbate + H2O	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.14.17.1	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.14.17.1	adrenal medulla	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.14.17.1	3,4-dihydroxyphenethylamine + ascorbate + O2	-	Bos taurus	noradrenaline + dehydroascorbate + H2O	-	?
1.14.17.1	3,4-dihydroxyphenethylamine + ascorbate + O2	-	Bos taurus	noradrenaline + dehydroascorbate + H2O	norepinephrine	?

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Release 2023.1 (January 2023)