EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.14.17 | 0.005 | - |
FAD | - |
Rattus norvegicus | |
1.14.14.17 | 0.013 | - |
squalene | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
1.14.14.17 | membrane | - |
Rattus norvegicus | 16020 | - |
1.14.14.17 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.17 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.14.14.17 | - |
Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.14.14.17 | liver | - |
Rattus norvegicus | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.14.14.17 | 0.00619 | - |
- |
Rattus norvegicus |
EC Number | Storage Stability | Organism |
---|---|---|
1.14.14.17 | -70°C, 50 mM Tris-HCl buffer, pH 7.4, 0.5% Triton X-100, several weeks | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.17 | (3S)-2,3-epoxy-2,3-dihydrosqualene + FAD + H2O | - |
Rattus norvegicus | squalene + FADH2 + O2 | - |
r | |
1.14.14.17 | squalene + NAD(P)H + O2 | - |
Rattus norvegicus | (S)-squalene-2,3-epoxide + NADP+ + H2O | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
1.14.14.17 | monomer | - |
Rattus norvegicus |
1.14.14.17 | More | enzyme system consists of squalene epoxidase which is distinct from hemoproteins such as cytochrome P-450 isozymes, and a flavoprotein identical with NADPH-cytochrome P-450 reductase | Rattus norvegicus |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.14.14.17 | 0.0055 | - |
squalene | - |
Rattus norvegicus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.17 | FAD | - |
Rattus norvegicus |