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Literature summary extracted from

  • Tenhunen, R.; Ross, M.E.; Marver, H.S.; Schmid, R.
    Reduced nicotinamide-adenine dinucleotide phosphate dependent biliverdin reductase: partial purification and characterization (1970), Biochemistry, 9, 298-303.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.1.24 albumin
-
Cavia porcellus

General Stability

EC Number General Stability Organism
1.3.1.24 repeated freeze-thawing: little loss of activity , no significant loss of activity, partially purified enzyme Cavia porcellus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.1.24 albumin
-
Cavia porcellus
1.3.1.24 bilirubin
-
Cavia porcellus
1.3.1.24 CuSO4
-
Cavia porcellus
1.3.1.24 Fe2+
-
Cavia porcellus
1.3.1.24 Fe3+
-
Cavia porcellus
1.3.1.24 iodoacetate
-
Cavia porcellus
1.3.1.24 lipase
-
Cavia porcellus
1.3.1.24 p-hydroxymercuribenzoate
-
Cavia porcellus
1.3.1.24 Trypsin
-
Cavia porcellus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.1.24 biliverdin + NAD(P)H Cavia porcellus physiologic degradation of heme to bile pigments bilirubin + NAD(P)+
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.24 Cavia porcellus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.1.24
-
Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.1.24 brain
-
Cavia porcellus
-
1.3.1.24 kidney
-
Cavia porcellus
-
1.3.1.24 liver
-
Cavia porcellus
-
1.3.1.24 muscle low activity Cavia porcellus
-
1.3.1.24 spleen
-
Cavia porcellus
-

Storage Stability

EC Number Storage Stability Organism
1.3.1.24 -20°C, 8 weeks, 1-10 mg protein per ml, 5-25% loss of activity, partially purified enzyme Cavia porcellus
1.3.1.24 0°C, 8 weeks, 1-10 mg protein per ml, 15-25% loss of activity Cavia porcellus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.24 biliverdin + NAD(P)H activity with NADPH is 50 times greater than with NADH Cavia porcellus bilirubin + NAD(P)+
-
?
1.3.1.24 biliverdin + NAD(P)H physiologic degradation of heme to bile pigments Cavia porcellus bilirubin + NAD(P)+
-
?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.3.1.24 56
-
5 min, complete loss of activity Cavia porcellus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.1.24 NADH
-
Cavia porcellus
1.3.1.24 NADPH
-
Cavia porcellus