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Literature summary extracted from

  • Tunnicliff, G.
    Action of inhibitors on brain glutamate decarboxylase (1990), Int. J. Biochem., 27, 1235-1241.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.15 2,6-pyridine dicarboxylic acid
-
 Rattus norvegicus
4.1.1.15 2-Methyl-3,4-didehydroglutamic acid
-
 Gallus gallus
4.1.1.15 3,4,5-Trihydroxybenzoic acid
-
 Mus musculus
4.1.1.15 3,4,5-Trihydroxybenzoic acid
-
 Rattus norvegicus
4.1.1.15 3,4-dihydroxybenzoic acid
-
 Mus musculus
4.1.1.15 3,4-dihydroxybenzoic acid
-
 Rattus norvegicus
4.1.1.15 3-Bromopyruvate
-
 Mus musculus
4.1.1.15 3-Mercaptopropionic acid
-
 Mus musculus
4.1.1.15 3-Mercaptopropionic acid
-
 Rattus norvegicus
4.1.1.15 4-Aminohex-5-ynoic acid
-
 Mus musculus
4.1.1.15 5,5'-dithiobis(2-nitrobenzoate)
-
 Mus musculus
4.1.1.15 5,5'-dithiobis(2-nitrobenzoate)
-
 Rattus norvegicus
4.1.1.15 Asp D-Asp, weak Mus musculus
4.1.1.15 Carbohydrazide
-
 Mus musculus
4.1.1.15 DL-4-Amino-4-phosphonobutyrate
-
 Mus musculus
4.1.1.15 DL-Penicillamine
-
 Mus musculus
4.1.1.15 Glutamate gamma-hydroxamate weak Mus musculus
4.1.1.15 Isonicotinic acid hydrazide
-
 Mus musculus
4.1.1.15 L-aspartate beta-hydroxamate weak Mus musculus
4.1.1.15 L-Glu weak Mus musculus
4.1.1.15 malate weak Mus musculus
4.1.1.15 additional information
-
 Mus musculus
4.1.1.15 p-hydroxymercuribenzoate
-
 Mus musculus
4.1.1.15 Phenylglyoxal
-
 Gallus gallus
4.1.1.15 Semicarbazide
-
 Mus musculus
4.1.1.15 Thiocarbohydrazide
-
 Mus musculus
4.1.1.15 Thiomalate
-
 Mus musculus
4.1.1.15 Thiosemicarbazide
-
 Mus musculus
4.1.1.15 Zn2+
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.15 Gallus gallus
-
-
-
4.1.1.15 Mus musculus
-
-
-
4.1.1.15 Rattus norvegicus
-
-
-
4.1.1.15 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.15 brain
-
 Mus musculus
-
4.1.1.15 brain
-
 Rattus norvegicus
-
4.1.1.15 brain
-
 Sus scrofa
-
4.1.1.15 embryo
-
 Gallus gallus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.15 L-Glu
-
 Gallus gallus 4-Aminobutanoate + CO2
-
 ?
4.1.1.15 L-Glu
-
 Mus musculus 4-Aminobutanoate + CO2
-
 ?
4.1.1.15 L-Glu
-
 Rattus norvegicus 4-Aminobutanoate + CO2
-
 ?
4.1.1.15 L-Glu
-
 Sus scrofa 4-Aminobutanoate + CO2
-
 ?