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Literature summary extracted from
- _ber eine Valin-carboxylase aus Bacillus sphaericus (1971), Arch. Mikrobiol., 79, 12-24.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.14 | pyridoxal | weak activation | Lysinibacillus sphaericus |  |
| 4.1.1.14 | pyridoxal phosphate | activates | Lysinibacillus sphaericus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.1.1.14 | AgNO3 | - |
Lysinibacillus sphaericus | |
| 4.1.1.14 | HgCl2 | - |
Lysinibacillus sphaericus | |
| 4.1.1.14 | hydroxylamine | - |
Lysinibacillus sphaericus | |
| 4.1.1.14 | iodoacetate | pyridoxal phosphate protects | Lysinibacillus sphaericus | |
| 4.1.1.14 | KCN | - |
Lysinibacillus sphaericus | |
| 4.1.1.14 | Penicillamine | - |
Lysinibacillus sphaericus | |
| 4.1.1.14 | Semicarbazide | - |
Lysinibacillus sphaericus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.1.14 | Lysinibacillus sphaericus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 4.1.1.14 | cell culture | highest activity in very young cultures, decreases rapidly in the early exponential phase of growth | Lysinibacillus sphaericus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.1.14 | Ala | - |
Lysinibacillus sphaericus | Ethylamine + CO2 | - |
? | |
| 4.1.1.14 | L-2-Aminobutanoate | - |
Lysinibacillus sphaericus | n-Propylamine + CO2 | - |
? | |
| 4.1.1.14 | L-Leu | - |
Lysinibacillus sphaericus | 3-Methylbutylamine + CO2 | - |
? | |
| 4.1.1.14 | L-Met | - |
Lysinibacillus sphaericus | 3-Methylmercaptopropylamine + CO2 | - |
? | |
| 4.1.1.14 | L-Norleucine | - |
Lysinibacillus sphaericus | Pentylamine + CO2 | - |
? | |
| 4.1.1.14 | L-Norvaline | - |
Lysinibacillus sphaericus | n-Butylamine + CO2 | - |
? | |
| 4.1.1.14 | L-Phe | - |
Lysinibacillus sphaericus | 2-phenylethylamine + CO2 | - |
? | |
| 4.1.1.14 | L-valine | - |
Lysinibacillus sphaericus | i-butylamine + CO2 | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.14 | 50 | 60 | L-Val | Lysinibacillus sphaericus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.14 | 70 | - |
10 min, 85% loss of activity | Lysinibacillus sphaericus |
| 4.1.1.14 | 80 | - |
10 min, complete inactivation | Lysinibacillus sphaericus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 4.1.1.14 | 7.7 | 7.9 | Val, Leu or Met | Lysinibacillus sphaericus |
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