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Literature summary extracted from

  • Bundy, B.M.; Campbell, A.L.; Neidle, E.L.
    Similarities between the antABC-encoded anthranilate dioxygenase and the benABC-encoded benzoate dioxygenase of Acinetobacter sp. strain ADP1 (1998), J. Bacteriol., 180, 4466-4474.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.12.1 clustered antABC genes from ADP1 chromosome encodes anthranilate dioxygenase Acinetobacter sp.

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.12.1 Fe2+ required Pseudomonas sp.
1.14.12.10 Iron reductase component contains a plant type [2Fe-2S] cluster and a presumed mononuclear iron, the terminal dioxygenase contains a Rieske-type [2Fe-2S] cluster Acinetobacter sp.

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.14.12.1 19000
-
 1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence Acinetobacter sp.
1.14.12.1 39000
-
 1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence Acinetobacter sp.
1.14.12.1 54000
-
 1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence Acinetobacter sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O Pseudomonas sp.
-
 catechol + CO2 + NAD(P)+ + NH3
-
 ?
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O Acinetobacter sp.
-
 catechol + CO2 + NAD(P)+ + NH3
-
 ?
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O Acinetobacter sp. ADP1
-
 catechol + CO2 + NAD(P)+ + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.12.1 Acinetobacter sp.
-
 derived from BD413
-
1.14.12.1 Acinetobacter sp. ADP1
-
 derived from BD413
-
1.14.12.1 Pseudomonas sp.
-
-
-
1.14.12.10 Acinetobacter sp.
-
 class IB dioxygenase
-
1.14.12.10 Acinetobacter sp. ADP1
-
 class IB dioxygenase
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O
-
 Pseudomonas sp. catechol + CO2 + NAD(P)+ + NH3
-
 ?
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O
-
 Acinetobacter sp. catechol + CO2 + NAD(P)+ + NH3
-
 ?
1.14.12.1 anthranilic acid + NAD(P)H + O2 + H2O
-
 Acinetobacter sp. ADP1 catechol + CO2 + NAD(P)+ + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
1.14.12.1 trimer 1 * 19000 + 1 * 39000 + 1 * 54000, DNA-sequence Acinetobacter sp.

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.12.10 FAD
-
 Acinetobacter sp.