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Literature summary extracted from
- Cytochrome c oxidase (1974), Mol. Mech. Oxygen Activ. (Hayaishi, O., ed.) Academic Press, New York, , 479-534.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | azide | - |
Bos taurus |  |
| 7.1.1.9 | azide | heme-binding inhibitor, noncompetitive vs. O2 and cytochrome c | eukaryota | |
| 7.1.1.9 | CN- | - |
Bos taurus | |
| 7.1.1.9 | CN- | heme-binding inhibitor, noncompetitive vs. O2 and cytochrome c | eukaryota | |
| 7.1.1.9 | CO | competitive vs. O2 | Bos taurus | |
| 7.1.1.9 | CO | competitive vs. O2 | eukaryota | |
| 7.1.1.9 | F- | - |
Bos taurus | |
| 7.1.1.9 | F- | - |
eukaryota | |
| 7.1.1.9 | ferricytochrome c | - |
eukaryota | |
| 7.1.1.9 | NO | competitive vs. O2 | Bos taurus | |
| 7.1.1.9 | phosphate | - |
Bos taurus | |
| 7.1.1.9 | Sulfide | - |
Bos taurus | |
| 7.1.1.9 | Sulfide | heme-binding inhibitor, noncompetitive vs. O2 and cytochrome c | eukaryota | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.1.1.9 | 0.006 | 0.077 | ferrocytochrome c | dependency on pH, phosphate and K+ concentration | Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 7.1.1.9 | 180000 | 280000 | minimal molecular weight, calculated from subunit composition, heme content | eukaryota |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.9 | Bos taurus | - |
- |
- |
| 7.1.1.9 | eukaryota | - |
- |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Bos taurus | ferricytochrome c + H2O | - |
r | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 7.1.1.9 | 40 | - |
- |
Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 7.1.1.9 | 6 | - |
- |
Bos taurus |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.1.1.9 | 0.0035 | - |
ferricytochrome c | at pH 8.0 | eukaryota | |
| 7.1.1.9 | 0.0079 | - |
ferricytochrome c | at pH 7.0 | eukaryota | |
| 7.1.1.9 | 0.0083 | - |
ferricytochrome c | at pH 6.0 | eukaryota | |
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Release 2023.1 (January 2023)
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