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Literature summary extracted from
- Cytochrome c oxidase in prokaryotes (1987), FEMS Microbiol. Rev., 46, 41-56.
No PubMed abstract available
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | cardiolipin | - |
Nitrobacter winogradskyi |  |
| 7.1.1.9 | cardiolipin | stimulation with non-physiological electron donors | Bacteria | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.1.1.9 | 0.00002 | - |
ferrocytochrome c | biphasic kinetic with 2 different Km values | Nitrobacter winogradskyi | |
| 7.1.1.9 | 0.002 | - |
ferrocytochrome c | - |
Bacillus subtilis | |
| 7.1.1.9 | 0.002 | - |
ferrocytochrome c | yeast cytochrome c | Thermus thermophilus | |
| 7.1.1.9 | 0.002 | 0.003 | ferrocytochrome c552 | - |
Thermus thermophilus | |
| 7.1.1.9 | 0.004 | - |
ferrocytochrome c | horse cytochrome c, in dodecylmaltoside | Paracoccus denitrificans | |
| 7.1.1.9 | 0.004 | - |
ferrocytochrome c | biphasic kinetic with 2 different Km values | Nitrobacter winogradskyi | |
| 7.1.1.9 | 0.01 | - |
ferrocytochrome c | yeast cytochrome c, approx. value | Cereibacter sphaeroides | |
| 7.1.1.9 | 0.011 | - |
ferrocytochrome c | - |
Starkeya novella | |
| 7.1.1.9 | 0.011 | - |
ferrocytochrome c552 | from Thermus thermophilus, bacterial enzyme | Bacteria | |
| 7.1.1.9 | 0.011 | - |
ferrocytochrome c552 | cytochrome c552 from Thermus thermophilus | Bacillus sp. PS3 | |
| 7.1.1.9 | 0.024 | - |
ferrocytochrome c | horse cytochrome c | Rhodobacter capsulatus | |
| 7.1.1.9 | 0.067 | - |
ferrocytochrome c551 | from thermophilic bacterium PS3, bacterial enzyme | Bacteria | |
| 7.1.1.9 | 0.067 | - |
ferrocytochrome c551 | cytochrome c551 from thermophilic bacterium PS3 | Bacillus sp. PS3 | |
| 7.1.1.9 | 0.13 | - |
ferrocytochrome c | from horse heart, bacterial enzyme | Bacteria | |
| 7.1.1.9 | 0.13 | - |
ferrocytochrome c | horse heart cytochrome c | Bacillus sp. PS3 | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.1.1.9 | cytoplasmic membrane | - |
Paracoccus denitrificans | - |
- |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | Cu | - |
Paracoccus denitrificans | |
| 7.1.1.9 | Cu | - |
Bacteria | |
| 7.1.1.9 | Cu | - |
Thermus thermophilus | |
| 7.1.1.9 | Cu | - |
Cereibacter sphaeroides | |
| 7.1.1.9 | Cu | - |
Starkeya novella | |
| 7.1.1.9 | Cu | - |
Bacillus sp. PS3 | |
| 7.1.1.9 | Cu | 2-3 Cu ions per complex of one subunit | Nitrobacter winogradskyi | |
| 7.1.1.9 | Fe | - |
Bacteria | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 7.1.1.9 | 22000 | - |
1 * 56000 + 1 * 38000 + 1 * 22000, SDS-PAGE, Ferguson plot | Bacillus sp. PS3 |
| 7.1.1.9 | 22000 | - |
1 * 57000 + 1 * 37000 + 1 * 22000, SDS-PAGE | Bacillus subtilis |
| 7.1.1.9 | 23000 | - |
1 * 23000 + 1 * 32000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | 23000 | - |
1 * 45000 + 1 * 28000 + 1 * 23000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | 23000 | - |
x * 32000 + x * 23000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | 28000 | - |
1 * 45000 + 1 * 28000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | 28000 | - |
1 * 45000 + 1 * 28000 + 1 * 23000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | 31000 | - |
1 * 51000 + 1 * 31000, SDS-PAGE, Ferguson plot | Nitrobacter winogradskyi |
| 7.1.1.9 | 32000 | - |
1 * 23000 + 1 * 32000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | 32000 | - |
x * 32000 + x * 23000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | 33000 | - |
1 * 55000 or 71000 + 1 * 33000, SDS-PAGE | Thermus thermophilus |
| 7.1.1.9 | 35000 | - |
1 * 35000 + 1 * 37000 + 1 * 45000, SDS-PAGE | Cereibacter sphaeroides |
| 7.1.1.9 | 37000 | - |
1 * 35000 + 1 * 37000 + 1 * 45000, SDS-PAGE | Cereibacter sphaeroides |
| 7.1.1.9 | 37000 | - |
1 * 57000 + 1 * 37000 + 1 * 22000, SDS-PAGE | Bacillus subtilis |
| 7.1.1.9 | 38000 | - |
1 * 56000 + 1 * 38000 + 1 * 22000, SDS-PAGE, Ferguson plot | Bacillus sp. PS3 |
| 7.1.1.9 | 45000 | - |
1 * 45000 + 1 * 28000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | 45000 | - |
1 * 45000 + 1 * 28000 + 1 * 23000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | 45000 | - |
1 * 35000 + 1 * 37000 + 1 * 45000, SDS-PAGE | Cereibacter sphaeroides |
| 7.1.1.9 | 51000 | - |
1 * 51000 + 1 * 31000, SDS-PAGE, Ferguson plot | Nitrobacter winogradskyi |
| 7.1.1.9 | 55000 | - |
1 * 55000 or 71000 + 1 * 33000, SDS-PAGE | Thermus thermophilus |
| 7.1.1.9 | 56000 | - |
1 * 56000 + 1 * 38000 + 1 * 22000, SDS-PAGE, Ferguson plot | Bacillus sp. PS3 |
| 7.1.1.9 | 57000 | - |
1 * 57000 + 1 * 37000 + 1 * 22000, SDS-PAGE | Bacillus subtilis |
| 7.1.1.9 | 65000 | - |
1 * 65000, b heme | Rhodobacter capsulatus |
| 7.1.1.9 | 115000 | - |
sedimentation analysis | Starkeya novella |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.1.1.9 | Bacillus sp. PS3 | - |
- |
- |
| 7.1.1.9 | Bacillus subtilis | - |
- |
- |
| 7.1.1.9 | Bacteria | - |
- |
- |
| 7.1.1.9 | Cereibacter sphaeroides | - |
- |
- |
| 7.1.1.9 | Nitrobacter winogradskyi | - |
- |
- |
| 7.1.1.9 | no activity in Escherichia coli | - |
- |
- |
| 7.1.1.9 | Paracoccus denitrificans | - |
- |
- |
| 7.1.1.9 | Rhodobacter capsulatus | - |
- |
- |
| 7.1.1.9 | Starkeya novella | - |
- |
- |
| 7.1.1.9 | Thermus thermophilus | - |
HB8 | - |
| 7.1.1.9 | Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | - |
HB8 | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 7.1.1.9 | - |
Paracoccus denitrificans |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.1.1.9 | ferrocytochrome c + O2 | - |
Paracoccus denitrificans | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | - |
Starkeya novella | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | - |
Nitrobacter winogradskyi | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | artificial electron donor: ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine | Bacteria | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | artificial electron donor: ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine | Bacillus subtilis | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | artificial electron donor: ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine | Thermus thermophilus | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | artificial electron donor: ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine | Bacillus sp. PS3 | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 | artificial electron donor: ascorbate/N,N,N',N'-tetramethyl-p-phenylenediamine | Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | ferricytochrome c + H2O | - |
? | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Paracoccus denitrificans | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Bacteria | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Bacillus subtilis | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Thermus thermophilus | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Cereibacter sphaeroides | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Rhodobacter capsulatus | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Starkeya novella | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Nitrobacter winogradskyi | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Bacillus sp. PS3 | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c + O2 + H+ | - |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | ferricytochrome c + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c551 + O2 + H+ | - |
Bacteria | ferricytochrome c551 + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c551 + O2 + H+ | - |
Bacillus sp. PS3 | ferricytochrome c551 + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c552 + O2 + H+ | - |
Bacteria | ferricytochrome c552 + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c552 + O2 + H+ | - |
Thermus thermophilus | ferricytochrome c552 + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c552 + O2 + H+ | - |
Bacillus sp. PS3 | ferricytochrome c552 + H2O | - |
r | |
| 7.1.1.9 | ferrocytochrome c552 + O2 + H+ | - |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | ferricytochrome c552 + H2O | - |
r | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 7.1.1.9 | ? | x * 32000 + x * 23000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | dimer | - |
Bacillus subtilis |
| 7.1.1.9 | dimer | 1 * 55000 or 71000 + 1 * 33000, SDS-PAGE | Thermus thermophilus |
| 7.1.1.9 | dimer | 1 * 51000 + 1 * 31000, SDS-PAGE, Ferguson plot | Nitrobacter winogradskyi |
| 7.1.1.9 | dimer | 1 * 45000 + 1 * 28000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | dimer | 1 * 23000 + 1 * 32000, SDS-PAGE | Starkeya novella |
| 7.1.1.9 | monomer | - |
Thermus thermophilus |
| 7.1.1.9 | monomer | 1 * 65000, b heme | Rhodobacter capsulatus |
| 7.1.1.9 | trimer | - |
Thermus thermophilus |
| 7.1.1.9 | trimer | 1 * 45000 + 1 * 28000 + 1 * 23000, SDS-PAGE | Paracoccus denitrificans |
| 7.1.1.9 | trimer | 1 * 35000 + 1 * 37000 + 1 * 45000, SDS-PAGE | Cereibacter sphaeroides |
| 7.1.1.9 | trimer | 1 * 56000 + 1 * 38000 + 1 * 22000, SDS-PAGE, Ferguson plot | Bacillus sp. PS3 |
| 7.1.1.9 | trimer | 1 * 57000 + 1 * 37000 + 1 * 22000, SDS-PAGE | Bacillus subtilis |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.1.1.9 | heme a | - |
Paracoccus denitrificans | |
| 7.1.1.9 | heme a | - |
Bacteria | |
| 7.1.1.9 | heme a | - |
Bacillus subtilis | |
| 7.1.1.9 | heme a | - |
Thermus thermophilus | |
| 7.1.1.9 | heme a | - |
Starkeya novella | |
| 7.1.1.9 | heme a | - |
Bacillus sp. PS3 | |
| 7.1.1.9 | heme a | 2 heme a per complex of one subunit | Nitrobacter winogradskyi | |
| 7.1.1.9 | Heme a3 | - |
Paracoccus denitrificans | |
| 7.1.1.9 | Heme a3 | - |
Bacteria | |
| 7.1.1.9 | Heme a3 | - |
Bacillus subtilis | |
| 7.1.1.9 | Heme a3 | - |
Thermus thermophilus | |
| 7.1.1.9 | Heme a3 | - |
Starkeya novella | |
| 7.1.1.9 | Heme a3 | - |
Nitrobacter winogradskyi | |
| 7.1.1.9 | Heme a3 | - |
Bacillus sp. PS3 | |
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