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Literature summary extracted from

  • Joo, H.S.; Kim, S.S.
    Purification and characterization of the catabolic alpha-acetolactate synthase from Serratia marcescens (1998), J. Biochem. Mol. Biol., 31, 37-43.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.2.1.6 Ile no inhibition Serratia marcescens
2.2.1.6 Leu no inhibition Serratia marcescens
2.2.1.6 Val no inhibition Serratia marcescens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.2.1.6 22.6
-
 pyruvate
-
 Serratia marcescens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.2.1.6 64000
-
 2 * 64000, SDS-PAGE Serratia marcescens
2.2.1.6 150000
-
-
 Serratia marcescens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.2.1.6 pyruvate Serratia marcescens the enzyme plays a role in not only preventing intracellular acidification but also supplying alpha-acetolactate as an intermediate of branched chain amino acids biosynthesis ?
-
 ?
2.2.1.6 pyruvate Serratia marcescens catabolic enzyme is involved in 2,3-butanediol pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.2.1.6 Serratia marcescens
-
 ATCC 25419
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.2.1.6
-
 Serratia marcescens

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.2.1.6 6.25
-
-
 Serratia marcescens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.2.1.6 pyruvate
-
 Serratia marcescens 2-acetolactate + CO2
-
 ?
2.2.1.6 pyruvate the enzyme plays a role in not only preventing intracellular acidification but also supplying alpha-acetolactate as an intermediate of branched chain amino acids biosynthesis Serratia marcescens ?
-
 ?
2.2.1.6 pyruvate catabolic enzyme is involved in 2,3-butanediol pathway Serratia marcescens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.2.1.6 dimer 2 * 64000, SDS-PAGE Serratia marcescens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.2.1.6 60
-
 30 min, stable Serratia marcescens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.2.1.6 5.5
-
-
 Serratia marcescens