Literature summary extracted from

Hillson, D.A.; Freedman, R.B.
Bovine liver thiol-protein disulphide oxidoreductases. An alternative method for differential purification and resolution of protein disulphide-isomerase and glutathione-insulin transhydrogenase (1980), Biochem. J., 191, 389-393.

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
1.8.4.2	37000	-	gel filtration	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.8.4.2	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.8.4.2	partially	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.8.4.2	liver	-	Bos taurus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
1.8.4.2	0.00081	-	-	Bos taurus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.8.4.2	GSH + insulin	-	Bos taurus	GSSG + reduced insulin chain A and B	-	?
1.8.4.2	GSH + protein disulfide	-	Bos taurus	GSSG + protein-dithiol	-	?
1.8.4.2	additional information	glutathione-insulin transhydrogenase EC 1.8.4.2 and protein disulfide-isomerase EC 5.3.4.1 activities are not both catalyzed by a single enzyme species	Bos taurus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.8.4.2	More	glutathione-insulin transhydrogenase EC 1.8.4.2 and protein disulfide-isomerase EC 5.3.4.1 activities are not both catalyzed by a single enzyme species	Bos taurus

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Release 2023.1 (January 2023)