Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Montrichard, F.; Le Guen, F.; Laval-Martin, D.L.; Davioud-Charvet, E.
    Evidence for the co-existence of glutathione reductase and trypanothione reductase in the non-trypanosomatid Euglenozoa: Euglena gracilis Z (1999), FEBS Lett., 442, 29-33.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.1.7 0.054
-
 GSSG
-
 Euglena gracilis
1.8.1.12 0.031
-
 trypanothione disulfide
-
 Euglena gracilis
1.8.1.12 0.091
-
 glutathionylspermidine disulfide
-
 Euglena gracilis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.1.7 cytoplasm
-
 Euglena gracilis 5737
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.1.7 50000
-
 2 * 50000, SDS-PAGE Euglena gracilis
1.8.1.12 54000
-
 x * 54000, SDS-PAGE Euglena gracilis

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.7 Euglena gracilis
-
 Z
-
1.8.1.7 Euglena gracilis Z
-
 Z
-
1.8.1.12 Euglena gracilis
-
 Z
-
1.8.1.12 Euglena gracilis Z
-
 Z
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.8.1.7
-
 Euglena gracilis
1.8.1.12
-
 Euglena gracilis

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.8.1.7 0.246
-
-
 Euglena gracilis
1.8.1.12 0.067
-
 crude extract Euglena gracilis
1.8.1.12 272
-
 purified enzyme Euglena gracilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.7 GSSG + NADPH highly specific for GSSG Euglena gracilis glutathione + NADP+
-
 ?
1.8.1.7 GSSG + NADPH highly specific for GSSG Euglena gracilis Z glutathione + NADP+
-
 ?
1.8.1.12 glutathionylspermidine disulfide + NADPH
-
 Euglena gracilis 2-glutathionylspermidine + NADP+
-
 ?
1.8.1.12 glutathionylspermidine disulfide + NADPH
-
 Euglena gracilis Z 2-glutathionylspermidine + NADP+
-
 ?
1.8.1.12 trypanothione disulfide + NADPH
-
 Euglena gracilis trypanothione + NADP+
-
 ?
1.8.1.12 trypanothione disulfide + NADPH
-
 Euglena gracilis Z trypanothione + NADP+
-
 ?

Subunits

EC Number Subunits Comment Organism
1.8.1.7 dimer 2 * 50000, SDS-PAGE Euglena gracilis
1.8.1.12 ? x * 54000, SDS-PAGE Euglena gracilis

Synonyms

EC Number Synonyms Comment Organism
1.8.1.7 GR
-
 Euglena gracilis
1.8.1.12 TR
-
 Euglena gracilis

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.8.1.7 317
-
 GSSG
-
 Euglena gracilis
1.8.1.12 242
-
 glutathionylspermidine disulfide
-
 Euglena gracilis
1.8.1.12 283
-
 trypanothione disulfide
-
 Euglena gracilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.7 NADPH best electron donor Euglena gracilis
1.8.1.12 FAD
-
 Euglena gracilis
1.8.1.12 NADH not Euglena gracilis
1.8.1.12 NADPH strictly dependent on Euglena gracilis