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Literature summary extracted from

  • Shigeoka, S.; Onishi, T.; Nakano, Y.; Kitaoka, S.
    Characterization and physiological function of glutathione reductase in Euglena gracilis z (1987), Biochem. J., 242, 511-515.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.8.1.7 Co2+
-
 Euglena gracilis
1.8.1.7 Cu2+
-
 Euglena gracilis
1.8.1.7 Fe3+
-
 Euglena gracilis
1.8.1.7 glutathione 1 mM Euglena gracilis
1.8.1.7 Hg2+
-
 Euglena gracilis
1.8.1.7 Mn2+
-
 Euglena gracilis
1.8.1.7 N-ethylmaleimide
-
 Euglena gracilis
1.8.1.7 NADP+ 1 mM Euglena gracilis
1.8.1.7 Ni2+
-
 Euglena gracilis
1.8.1.7 p-chloromercuribenzoate
-
 Euglena gracilis
1.8.1.7 Zn2+
-
 Euglena gracilis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.8.1.7 additional information
-
 additional information
-
 Euglena gracilis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.8.1.7 cytoplasm solely in cytoplasm Euglena gracilis 5737
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.8.1.7 40000
-
 2 * 40000, SDS-PAGE Euglena gracilis
1.8.1.7 79000
-
 gel filtration Euglena gracilis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.1.7 GSSG + NADPH Euglena gracilis
-
 glutathione + NADP+
-
 ir
1.8.1.7 GSSG + NADPH Euglena gracilis Z
-
 glutathione + NADP+
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
1.8.1.7 Euglena gracilis
-
 Z
-
1.8.1.7 Euglena gracilis Z
-
 Z
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Storage Stability

EC Number Storage Stability Organism
1.8.1.7 -20°C, several weeks Euglena gracilis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.1.7 GSSG + NADPH
-
 Euglena gracilis glutathione + NADP+
-
 ir
1.8.1.7 GSSG + NADPH highly specific for GSSG Euglena gracilis glutathione + NADP+
-
 ir
1.8.1.7 GSSG + NADPH
-
 Euglena gracilis Z glutathione + NADP+
-
 ir
1.8.1.7 GSSG + NADPH highly specific for GSSG Euglena gracilis Z glutathione + NADP+
-
 ir

Subunits

EC Number Subunits Comment Organism
1.8.1.7 dimer 2 * 40000, SDS-PAGE Euglena gracilis

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
1.8.1.7 67
-
 pH 5.8-8.4, stable Euglena gracilis
1.8.1.7 78
-
 pH 5. 8-8.4, unstable Euglena gracilis

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
1.8.1.7 5.8 8.4 67°C: stable, 78°C: unstable Euglena gracilis

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.1.7 NADH 1.3% activity of that with NADPH Euglena gracilis
1.8.1.7 NADPH best electron donor Euglena gracilis