BRENDA - Enzyme Database

Purification and properties of mitochondrial monoamine oxidase type A from human placenta

Weyler, W.; Salach, J.I.; J. Biol. Chem. 260, 13199-13207 (1985)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.3.4
2,2'-dipyridyl disulfide
-
Homo sapiens
1.4.3.4
amphetamine
a competitive inhibitor of MAO-A
Homo sapiens
1.4.3.4
Clorgyline
-
Homo sapiens
1.4.3.4
Deprenyl
-
Homo sapiens
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.4.3.4
additional information
-
additional information
Km of membrane-bound and Triton X-100-solubilized enzyme
Homo sapiens
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.4.3.4
mitochondrion
-
Homo sapiens
5739
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
Homo sapiens
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
RCHO + NH3 + H2O2
-
Homo sapiens
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
1.4.3.4
Homo sapiens
-
-
-
Purification (Commentary)
EC Number
Commentary
Organism
1.4.3.4
-
Homo sapiens
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
1.4.3.4
placenta
-
Homo sapiens
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.4.3.4
kynuramine + H2O + O2
-
394568
Homo sapiens
3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
394568
Homo sapiens
?
1.4.3.4
RCH2NH2 + H2O + O2
-
394568
Homo sapiens
RCHO + NH3 + H2O2
-
-
-
?
1.4.3.4
RCH2NH2 + H2O + O2
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
394568
Homo sapiens
RCHO + NH3 + H2O2
-
394568
Homo sapiens
?
Subunits
EC Number
Subunits
Commentary
Organism
1.4.3.4
?
x * 60000-64000, SDS-PAGE
Homo sapiens
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.4.3.4
2.08
-
kynuramine
MAO-A
Homo sapiens
Cofactor
EC Number
Cofactor
Commentary
Organism
Structure
1.4.3.4
flavin
1 flavin per subunit; flavoprotein
Homo sapiens
Ki Value [mM]
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
1.4.3.4
0.02
-
amphetamine
-
Homo sapiens
Cofactor (protein specific)
EC Number
Cofactor
Commentary
Organism
Structure
1.4.3.4
flavin
1 flavin per subunit; flavoprotein
Homo sapiens
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
1.4.3.4
2,2'-dipyridyl disulfide
-
Homo sapiens
1.4.3.4
amphetamine
a competitive inhibitor of MAO-A
Homo sapiens
1.4.3.4
Clorgyline
-
Homo sapiens
1.4.3.4
Deprenyl
-
Homo sapiens
Ki Value [mM] (protein specific)
EC Number
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
1.4.3.4
0.02
-
amphetamine
-
Homo sapiens
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.4.3.4
additional information
-
additional information
Km of membrane-bound and Triton X-100-solubilized enzyme
Homo sapiens
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
1.4.3.4
mitochondrion
-
Homo sapiens
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1.4.3.4
RCH2NH2 + H2O + O2
Homo sapiens
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
RCHO + NH3 + H2O2
-
Homo sapiens
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
1.4.3.4
-
Homo sapiens
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
1.4.3.4
placenta
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1.4.3.4
kynuramine + H2O + O2
-
394568
Homo sapiens
3-(2-aminophenyl)-3-oxopropanal + NH3 + H2O2
-
394568
Homo sapiens
?
1.4.3.4
RCH2NH2 + H2O + O2
-
394568
Homo sapiens
RCHO + NH3 + H2O2
-
-
-
?
1.4.3.4
RCH2NH2 + H2O + O2
important functions in the metabolism of biogenic amines in the central nervous system and peripheral tissues
394568
Homo sapiens
RCHO + NH3 + H2O2
-
394568
Homo sapiens
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
1.4.3.4
?
x * 60000-64000, SDS-PAGE
Homo sapiens
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
1.4.3.4
2.08
-
kynuramine
MAO-A
Homo sapiens