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Literature summary extracted from

  • Bernheim, M.L.C.
    The reduction of hydroxylamine and some aryl hydroxamates by liver mitochondria from mammals and birds (1972), Enzymologia, 43, 167-176.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.7.1.10 Bromelain
-
 Rattus norvegicus
1.7.1.10 butanol
-
 Rattus norvegicus
1.7.1.10 CaCl2 reactivation by washing Rattus norvegicus
1.7.1.10 deoxycholic acid
-
 Rattus norvegicus
1.7.1.10 Duponol C
-
 Rattus norvegicus
1.7.1.10 ethanol
-
 Rattus norvegicus
1.7.1.10 KCl reactivation by washing Rattus norvegicus
1.7.1.10 Murine phospholipase
-
 Rattus norvegicus
1.7.1.10 N-Methyl hydroxylamine
-
 Rattus norvegicus
1.7.1.10 NaCl reactivation by washing Rattus norvegicus
1.7.1.10 papain
-
 Rattus norvegicus
1.7.1.10 phosphate
-
 Rattus norvegicus
1.7.1.10 Propanol
-
 Rattus norvegicus
1.7.1.10 Sodium arsenate
-
 Rattus norvegicus
1.7.1.10 Subtilopeptidase A
-
 Rattus norvegicus
1.7.1.10 Trypsin
-
 Rattus norvegicus
1.7.1.10 Uranyl acetate ATP, ADP, sodium diphosphate restores activity Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.7.1.10 membrane firmly attached to mitochondrial membrane Rattus norvegicus 16020
-
1.7.1.10 mitochondrion
-
 Mus musculus 5739
-
1.7.1.10 mitochondrion
-
 Sus scrofa 5739
-
1.7.1.10 mitochondrion
-
 Oryctolagus cuniculus 5739
-
1.7.1.10 mitochondrion
-
 Ovis aries 5739
-
1.7.1.10 mitochondrion
-
 Didelphidae 5739
-
1.7.1.10 mitochondrion firmly attached to membrane Rattus norvegicus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.7.1.10 Bos taurus
-
-
-
1.7.1.10 Canis lupus familiaris
-
-
-
1.7.1.10 Cavia porcellus
-
-
-
1.7.1.10 Cricetinae
-
-
-
1.7.1.10 Didelphidae
-
 very low activity
-
1.7.1.10 Gallus gallus
-
-
-
1.7.1.10 Mus musculus
-
-
-
1.7.1.10 no activity in Amphibia
-
-
-
1.7.1.10 no activity in fish
-
-
-
1.7.1.10 no activity in reptilia
-
-
-
1.7.1.10 Oryctolagus cuniculus
-
-
-
1.7.1.10 Ovis aries
-
-
-
1.7.1.10 Pigeon
-
-
-
1.7.1.10 Rattus norvegicus
-
-
-
1.7.1.10 Sus scrofa
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Gallus gallus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Cavia porcellus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Mus musculus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Rattus norvegicus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Bos taurus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Oryctolagus cuniculus
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Ovis aries
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Pigeon
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Canis lupus familiaris
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Didelphidae
a
1.7.1.10 NH3 + NAD+ + H2O = hydroxylamine + NADH + H+ also acts on hydroxamates Cricetinae
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.7.1.10 liver
-
 Mus musculus
-
1.7.1.10 liver
-
 Rattus norvegicus
-
1.7.1.10 liver
-
 Sus scrofa
-
1.7.1.10 liver
-
 Oryctolagus cuniculus
-
1.7.1.10 liver
-
 Ovis aries
-
1.7.1.10 liver
-
 Canis lupus familiaris
-
1.7.1.10 liver
-
 Didelphidae
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Gallus gallus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Cavia porcellus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Mus musculus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Rattus norvegicus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Bos taurus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Oryctolagus cuniculus anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Ovis aries anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Pigeon anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Canis lupus familiaris anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Didelphidae anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 anthranillic hydroxamate + NADH + H+ activity in liver mitochondria Cricetinae anthranilamide + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Gallus gallus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Cavia porcellus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Mus musculus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Sus scrofa NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Bos taurus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Oryctolagus cuniculus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Ovis aries NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Pigeon NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Canis lupus familiaris NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Didelphidae NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH
-
 Cricetinae NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH very low activity with phenylhydroxylamine Rattus norvegicus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 hydroxylamine + NADH no reduction of N,N-diethyl or O-methyl compounds Rattus norvegicus NH3 + NAD+ + H2O
-
 ?
1.7.1.10 N-methylhydroxylamine + NADH
-
 Rattus norvegicus methylamine + NAD+ + H2O
-
 ?
1.7.1.10 N-methylhydroxylamine + NADH
-
 Sus scrofa methylamine + NAD+ + H2O
-
 ?
1.7.1.10 phenylhydroxylamine + NADH
-
 Rattus norvegicus phenylamine + NAD+ + H2O
-
 ?
1.7.1.10 phenylhydroxylamine + NADH
-
 Sus scrofa phenylamine + NAD+ + H2O
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.7.1.10 NADH
-
 Gallus gallus
1.7.1.10 NADH
-
 Cavia porcellus
1.7.1.10 NADH
-
 Mus musculus
1.7.1.10 NADH
-
 Rattus norvegicus
1.7.1.10 NADH
-
 Sus scrofa
1.7.1.10 NADH
-
 Bos taurus
1.7.1.10 NADH
-
 Oryctolagus cuniculus
1.7.1.10 NADH
-
 Ovis aries
1.7.1.10 NADH
-
 Pigeon
1.7.1.10 NADH
-
 Canis lupus familiaris
1.7.1.10 NADH
-
 Didelphidae
1.7.1.10 NADH
-
 Cricetinae