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Literature summary extracted from
- Subcellular localization of a glutathione-dependent dehydroascorbate reductase within specific rat brain regions (2001), Neuroscience, 104, 15-31.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 1.8.5.1 | basal plasma membrane | of blood vessels | Rattus norvegicus | 9925 | - |
| 1.8.5.1 | cytosol | of neurons, perinuclear position | Rattus norvegicus | 5829 | - |
| 1.8.5.1 | cytosol | perinuclear position, in neurons | Rattus norvegicus | 5829 | - |
| 1.8.5.1 | nuclear membrane | - |
Rattus norvegicus | 31965 | - |
| 1.8.5.1 | nucleus | - |
Rattus norvegicus | 5634 | - |
| 1.8.5.1 | nucleus | of neurons | Rattus norvegicus | 5634 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.5.1 | glutathione + dehydroascorbate | Rattus norvegicus | regenerates ascorbate after it is oxidized during normal aerobic metabolism | GSSG + ascorbate | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.8.5.1 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.8.5.1 | astrocyte | perivascular | Rattus norvegicus | - |
| 1.8.5.1 | blood vessel | basal membrane | Rattus norvegicus | - |
| 1.8.5.1 | brain | - |
Rattus norvegicus | - |
| 1.8.5.1 | cerebellum | myelin sheet | Rattus norvegicus | - |
| 1.8.5.1 | cerebellum | within the myelin sheets | Rattus norvegicus | - |
| 1.8.5.1 | corpus striatum | myelin sheet | Rattus norvegicus | - |
| 1.8.5.1 | endothelial cell | from striatum | Rattus norvegicus | - |
| 1.8.5.1 | myelin sheath | of striatum and cerebellum | Rattus norvegicus | - |
| 1.8.5.1 | neostriatum | within the myelin sheets | Rattus norvegicus | - |
| 1.8.5.1 | neuron | - |
Rattus norvegicus | - |
| 1.8.5.1 | perivascular astrocyte | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.8.5.1 | glutathione + dehydroascorbate | regenerates ascorbate after it is oxidized during normal aerobic metabolism | Rattus norvegicus | GSSG + ascorbate | - |
? | |
| 1.8.5.1 | GSH + dehydroascorbate | - |
Rattus norvegicus | GSSG + ascorbate | - |
? | |
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Release 2023.1 (January 2023)
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