EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.4 | p-Aminophenyldichloroarsine | inactivated only in presence of NADH and dihydrolipoamide, no significant loss of activity in absence of NADH and dihydrolipoamide | Thermoplasma acidophilum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.4 | 0.52 | - |
NAD+ | - |
Thermoplasma acidophilum | |
1.8.1.4 | 0.83 | - |
dihydrolipoamide | - |
Thermoplasma acidophilum |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
1.8.1.4 | 118000 | - |
gel filtration | Thermoplasma acidophilum |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.4 | additional information | Thermoplasma acidophilum | the enzyme fulfills its function in the pyruvate, 2-oxoglutarate and branched-chain 2-oxoacid dehydrogenase complexes and in the glycine cleavage system | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.4 | Thermoplasma acidophilum | - |
- |
- |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
1.8.1.4 | 0.012 | - |
- |
Thermoplasma acidophilum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.1.4 | dihydrolipoamide + NAD+ | alternate oxidation and reduction of an intrachain disulfide bond | Thermoplasma acidophilum | lipoamide + NADH | - |
? | |
1.8.1.4 | additional information | the enzyme fulfills its function in the pyruvate, 2-oxoglutarate and branched-chain 2-oxoacid dehydrogenase complexes and in the glycine cleavage system | Thermoplasma acidophilum | ? | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.4 | NAD+ | - |
Thermoplasma acidophilum |