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Literature summary extracted from

  • Lang, H.; Polster, M.; Brandsch, R.
    Rat liver dimethylglycine dehydrogenase. Flavinylation of the enzyme in hepatocytes in primary culture and characterization of a cDNA clone (1991), Eur. J. Biochem., 198, 793-799.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.5.8.4 screening of a cDNA library prepared in Escherichia coli from rat liver polyA RNA in the plasmid vector peD-X Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.5.8.4 mitochondrion
-
Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.8.4 N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor Rattus norvegicus reaction of the choline degradation pathway sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
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Organism

EC Number Organism UniProt Comment Textmining
1.5.8.4 Rattus norvegicus Q63342
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.8.4 liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.8.4 N,N-dimethylglycine + tetrahydropteroylpentaglutamate + acceptor reaction of the choline degradation pathway Rattus norvegicus sarcosine + 5,10-methylene tetrahydropteroylpentaglutamate + reduced acceptor
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Cofactor

EC Number Cofactor Comment Organism Structure
1.5.8.4 FAD covalently bound Rattus norvegicus