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Literature summary extracted from

  • Green, J.M.; Ballou, D.P.; Matthews, R.G.
    Examination of the role of methylenetetrahydrofolate reductase in incorporation of methyltetrahydrofolate into cellular metabolism (1988), FASEB J., 2, 42-47.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.20 NADPH 100 mM Sus scrofa
1.5.1.20 Polyglutamate analogues
-
 Sus scrofa
1.5.1.20 S-adenosylmethionine 0.05 mM Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.5.1.20 0.0019
-
 5-methyltetrahydropteroylhexaglutamate
-
 Sus scrofa
1.5.1.20 0.033
-
 5-methyltetrahydropteroylmonoglutamate
-
 Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.5.1.20 5,10-methylenetetrahydrofolate + NADPH Sus scrofa overview: role in incorporation of methyltetrahydrofolate into cellular metabolism ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.20 Sus scrofa
-
 overview
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.5.1.20 5,10-methylenetetrahydrofolate + NADPH overview: role in incorporation of methyltetrahydrofolate into cellular metabolism Sus scrofa ?
-
 ?
1.5.1.20 5-methyltetrahydropteroylmonoglutamate + 5,10-methylenetetrahydropteroylhexaglutamate
-
 Sus scrofa 5,10-methylenetetrahydropteroylmonoglutamate + 5-methyltetrahydropteroylhexaglutamate
-
 r