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Literature summary extracted from

  • Menzel, R.; Roth, J.
    Enzymatic properties of the purified putA protein from Salmonella typhimurium (1981), J. Biol. Chem., 256, 9762-9766.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.2.1.88 EDTA slight inhibition Salmonella enterica subsp. enterica serovar Typhimurium
1.2.1.88 ethylene glycol
-
 Salmonella enterica subsp. enterica serovar Typhimurium
1.2.1.88 Tween 20
-
 Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.88 additional information
-
 additional information
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.88 membrane
-
 Salmonella enterica subsp. enterica serovar Typhimurium 16020
-

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.88 Salmonella enterica subsp. enterica serovar Typhimurium
-
 putA gene product: enzyme with 2 activities: proline oxidase and 1-pyrroline-5-carboxylate dehydrogenase, which require different reaction conditions
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.2.1.88 L-glutamate 5-semialdehyde + NAD+ + H2O = L-glutamate + NADH + H+ ordered reaction mechanism Salmonella enterica subsp. enterica serovar Typhimurium
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.88 1-pyrroline-5-carboxylate + NAD+ + H2O
-
 Salmonella enterica subsp. enterica serovar Typhimurium L-glutamate + NADH
-
 ir
1.2.1.88 additional information enzyme with 2 activities: proline oxidase and 1-pyrroline-5-carboxylate dehydrogenase, which require different reaction conditions Salmonella enterica subsp. enterica serovar Typhimurium ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.88 NAD+
-
 Salmonella enterica subsp. enterica serovar Typhimurium