Literature summary extracted from

Yamada, H.; Yasunobu, K.T.
Monoamine oxidase II. Copper, one of the prosthetic groups of plasma monamine oxidase (1962), J. Biol. Chem., 237, 3077-3082.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.4.3.21	1,4-phenanthroline	0.0075 mM, 41% inhibition	Bos taurus
1.4.3.21	8-hydroxyquinoline	0.0075 mM, 27% inhibition	Bos taurus
1.4.3.21	Cupricin	-	Bos taurus
1.4.3.21	Cuprizone	copper chelating, 0.006 mM, 98% inhibition, competitive vs. benzylamine	Bos taurus
1.4.3.21	cyanide	0.1 mM, 76% inhibition	Bos taurus
1.4.3.21	Sodium thioglycolate	slight	Bos taurus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.4.3.21	1.49	-	benzylamine	-	Bos taurus

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.4.3.21	copper	copper protein	Bos taurus
1.4.3.21	copper	3.7 gatom of copper per mol of enzyme	Bos taurus
1.4.3.21	copper	contains cupric copper	Bos taurus
1.4.3.21	copper	copper involved in enzyme activity	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.4.3.21	Bos taurus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
1.4.3.21	-	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.4.3.21	blood plasma	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.4.3.21	benzylamine + H2O + O2	-	Bos taurus	benzaldehyde + NH3 + H2O2	-	?
1.4.3.21	RCH2NH2 + H2O + O2	-	Bos taurus	RCHO + NH3 + H2O2	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
1.4.3.21	0.014	-	Cuprizone	-	Bos taurus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)