Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Harris, E.D.; Gonnerman, W.A.; Savage, J.E.; O'Dell, B.L.
    Connective tissue amine oxidase. II. Purification and partial characterization of lysyl oxidase from chick aorta (1974), Biochim. Biophys. Acta, 341, 332-344.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.4.3.13 pyridoxal pyridoxal phosphate or closely related compound Gallus gallus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.4.3.13 2-mercaptoethanol weakly inhibitory Gallus gallus
1.4.3.13 beta-aminopropionitrile total inhibition at 1 mM Gallus gallus
1.4.3.13 diethyldithiocarbamate
-
Gallus gallus
1.4.3.13 dithiothreitol
-
Gallus gallus
1.4.3.13 hydroxylamine
-
Gallus gallus
1.4.3.13 phenylhydrazine
-
Gallus gallus
1.4.3.13 Semicarbazide
-
Gallus gallus
1.4.3.13 Zn2+ slightly inhibitory Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.4.3.13 Cu2+ copper metalloenzyme contains 0.14% copper, important for enzymatic function Gallus gallus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.4.3.13 59000
-
x * 59000, x * 61000, SDS-PAGE, may be isoenzymes or heterologous subunits Gallus gallus
1.4.3.13 61000
-
x * 59000, x * 61000, SDS-PAGE, may be isoenzymes or heterologous subunits Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
1.4.3.13 Gallus gallus
-
embryo
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.4.3.13 affinity, ion-exchange Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.4.3.13 aorta
-
Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.4.3.13 additional information
-
46390 cpm/mg Gallus gallus

Storage Stability

EC Number Storage Stability Organism
1.4.3.13 -15°C, powdered tissue, full enzyme activity for at least 4 months Gallus gallus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.4.3.13 peptidyl-L-hydroxylysyl-peptide + O2 + H2O
-
Gallus gallus peptidyl-L-2-amino-5-hydroxy-6-oxohexanoyl-peptide + NH3 + H2O2
-
?
1.4.3.13 peptidyl-L-lysyl-peptide + O2 + H2O part of elastin and collagen Gallus gallus peptidyl-L-allysyl-peptide + NH3 + H2O2
-
?

Subunits

EC Number Subunits Comment Organism
1.4.3.13 ? x * 59000, x * 61000, SDS-PAGE, may be isoenzymes or heterologous subunits Gallus gallus

Synonyms

EC Number Synonyms Comment Organism
1.4.3.13 lysyl oxidase amine oxidase, oxidative deamination Gallus gallus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.4.3.13 37
-
assay at Gallus gallus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.4.3.13 7.7
-
assay at Gallus gallus