Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Besrat, A.; Polan, C.E.; Henderson, L.M.
    Mammalian metabolism of glutaric acid (1969), J. Biol. Chem., 244, 1461-1467.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.3.8.6 FAD exogenous Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.8.6 Co2+
-
 Bos taurus
1.3.8.6 Cu2+
-
 Bos taurus
1.3.8.6 glutaconyl-CoA
-
 Bos taurus
1.3.8.6 p-chloromercuribenzoate
-
 Bos taurus
1.3.8.6 Zn2+
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.8.6 0.0012 0.01 glutaryl-CoA
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.6 mitochondrion
-
 Bos taurus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.3.8.6 200000
-
 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.6 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.8.6 partial Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.6 kidney
-
 Bos taurus
-
1.3.8.6 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.6 glutaryl-CoA + acceptor acceptors: electron-transfer flavoprotein, phenylmethylsulfonyl fluoride, 2,6-dichlorophenolindophenol, phenazine methosulfate, methylene blue Bos taurus crotonyl-CoA + CO2 + reduced acceptor
-
 ?
1.3.8.6 glutarylpantetheine + acceptor
-
 Bos taurus crotonylpantetheine + reduced acceptor
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.3.8.6 7.5 8 glutaryl-CoA + methylene blue Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
1.3.8.6 FAD
-
 Bos taurus