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Literature summary extracted from

  • Chalmers, R.A.; English, N.
    Fatty acid oxidation in cultured skin fibroblasts from patients with inherited disorders of fatty acid metabolism: studies on the specificity of acyl-CoA dehydrogenases (1987), Biochem. Soc. Trans., 15, 489-491.
No PubMed abstract available

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.8 mitochondrion
-
 Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.3.8.7 acyl-CoA + electron transfer flavoprotein Homo sapiens first step in beta-oxidation of fatty acids 2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.7 Homo sapiens
-
 skin fibroblast cell lines from healthy subjects and from patients with medium-chain, long-chain and with multiple-chain acyl-CoA dehydrogenase deficiency
-
1.3.8.8 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.7 skin fibroblast
-
 Homo sapiens
-
1.3.8.8 liver
-
 Homo sapiens
-
1.3.8.8 skin fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.7 acyl-CoA + acceptor specific for chain lengths C6-C8 Homo sapiens 2,3-dehydroacyl-CoA + reduced acceptor
-
 ?
1.3.8.7 acyl-CoA + electron transfer flavoprotein first step in beta-oxidation of fatty acids Homo sapiens 2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein
-
 ?
1.3.8.7 n-octanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol fibroblast medium-chain acyl-CoA dehydrogenase is specific towards C6-C8 acyl-CoA esters Homo sapiens 2-octenoyl-CoA + reduced acceptor
-
 ?
1.3.8.8 decanoyl-CoA + electron-transfer flavoprotein
-
 Homo sapiens 2-decenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
1.3.8.8 dodecanoyl-CoA + electron-transfer flavoprotein
-
 Homo sapiens 2-dodecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
1.3.8.8 palmitoyl-CoA + electron-transfer flavoprotein
-
 Homo sapiens 2-hexadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
1.3.8.8 stearoyl-CoA + electron-transfer flavoprotein
-
 Homo sapiens 2-octadecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?
1.3.8.8 tetradecanoyl-CoA + electron-transfer flavoprotein
-
 Homo sapiens 2-tetradecenoyl-CoA + reduced electron-transfer flavoprotein
-
 ?