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Literature summary extracted from

  • Davidson, B.; Schulz, H.
    Separation, properties, and regulation of acyl coenzyme A dehydrogenases from bovine heart and liver (1982), Arch. Biochem. Biophys., 213, 155-162.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.3.8.1 acetoacetyl-CoA
-
 Bos taurus
1.3.8.7 2-decenoyl-CoA medium- and long-chain acyl-CoA dehydrogenase Bos taurus
1.3.8.7 3-ketodecanoyl-CoA medium- and long-chain acyl-CoA dehydrogenase Bos taurus
1.3.8.7 DL-3-hydroxydecenoyl-CoA
-
 Bos taurus
1.3.8.7 additional information not inhibited by ATP, ADP, GTP, GDP, FAD, NAD+, NADP+, carnitine, acetyl-CoA, succinyl-CoA, citrate, isocitrate, succinate, alpha-ketoglutarate, malate, fumarate Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.3.8.1 0.003
-
 butyryl-CoA
-
 Bos taurus
1.3.8.1 0.012
-
 hexanoyl-CoA
-
 Bos taurus
1.3.8.7 0.0007
-
 decanoyl-CoA
-
 Bos taurus
1.3.8.7 0.002
-
 octanoyl-CoA
-
 Bos taurus
1.3.8.7 0.0035
-
 hexanoyl-CoA
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.3.8.1 mitochondrion
-
 Bos taurus 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.3.8.1 Bos taurus
-
-
-
1.3.8.7 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.3.8.1
-
 Bos taurus
1.3.8.7
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.3.8.1 heart
-
 Bos taurus
-
1.3.8.1 liver
-
 Bos taurus
-
1.3.8.7 heart
-
 Bos taurus
-
1.3.8.7 liver
-
 Bos taurus
-

Storage Stability

EC Number Storage Stability Organism
1.3.8.1 -76°C Bos taurus
1.3.8.7 -76°C Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.8.1 butyryl-CoA + electron acceptor
-
 Bos taurus 2-butenoyl-CoA + reduced acceptor
-
 ?
1.3.8.1 hexanoyl-CoA + phenazine methosulfate + dichloroindophenol
-
 Bos taurus 2-hexenoyl-CoA + reduced acceptor
-
 ?
1.3.8.7 decanoyl-CoA + phenazine methosulfate + 2,6-dichloroindophenol
-
 Bos taurus 2-trans-decenoyl-CoA + reduced acceptor
-
 ?
1.3.8.7 hexanoyl-CoA + 2,6-dichlorophenolindophenol
-
 Bos taurus trans-hex-2-enoyl-CoA + reduced 2,6-dichlorophenolindophenol
-
 r

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
1.3.8.1 0.01
-
 acetoacetyl-CoA
-
 Bos taurus
1.3.8.7 0.0007
-
 3-oxodecanoyl-CoA
-
 Bos taurus