EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.2.7.4 | butyryl-CoA | - |
Moorella thermoacetica | |
1.2.7.4 | CoASH | - |
Moorella thermoacetica | |
1.2.7.4 | crotonyl-CoA | - |
Moorella thermoacetica | |
1.2.7.4 | dephospho-CoASH | - |
Moorella thermoacetica | |
1.2.7.4 | desulfo-CoA | - |
Moorella thermoacetica | |
1.2.7.4 | pivaloylpantetheine-SH | - |
Moorella thermoacetica | |
1.2.7.4 | propionyl-CoA | - |
Moorella thermoacetica |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.7.4 | 0.01 | - |
CO | CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 0.6 | - |
acetyl-CoA | CO/acetyl-CoA exchange reaction | Moorella thermoacetica |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.7.4 | CO + H2O + electron acceptor | Moorella thermoacetica | catalyzes the final step in the synthesis of acetyl-CoA | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.2.7.4 | Moorella thermoacetica | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.2.7.4 | CO + H2O + electron acceptor | catalyzes the final step in the synthesis of acetyl-CoA | Moorella thermoacetica | ? | - |
? | |
1.2.7.4 | CO + H2O + methyl viologen | catalyzes the synthesis of acetyl-CoA from methyl corrinoid, Co and CoASH | Moorella thermoacetica | CO2 + reduced methyl viologen | - |
? | |
1.2.7.4 | CO + H2O + methyl viologen | catalyzes an exchange reaction between CO and the carbonyl group of acetyl-CoA | Moorella thermoacetica | CO2 + reduced methyl viologen | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.7.4 | 1.17 | - |
CO | - |
Moorella thermoacetica | |
1.2.7.4 | 7.33 | - |
CO | acetyl-CoA/CO exchange reaction | Moorella thermoacetica |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.2.7.4 | 0.007 | - |
CoASH | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 0.035 | - |
dephospho-CoASH | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 1.2 | - |
pivaloylpantetheine-SH | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 1.3 | - |
propionyl-CoA | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 1.4 | - |
crotonyl-CoA | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 1.45 | - |
butyryl-CoA | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica | |
1.2.7.4 | 6 | - |
desulfo-CoA | inhibition of CO/acetyl-CoA exchange reaction | Moorella thermoacetica |