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Literature summary extracted from

  • Ueda, M.; Tanaka, A.
    Long-chain aldehyde dehydrogenase of Candida Yeast (1990), Methods Enzymol., 188, 176-178.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.48 microsome
-
Yarrowia lipolytica
-
-
1.2.1.48 microsome
-
Candida tropicalis
-
-
1.2.1.48 mitochondrion
-
Yarrowia lipolytica 5739
-
1.2.1.48 mitochondrion
-
Candida tropicalis 5739
-
1.2.1.48 peroxisome
-
Yarrowia lipolytica 5777
-
1.2.1.48 peroxisome
-
Candida tropicalis 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.48 long-chain aldehyde + NAD+ Yarrowia lipolytica in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ Candida tropicalis in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ Yarrowia lipolytica in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ Candida tropicalis in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.48 Candida tropicalis
-
-
-
1.2.1.48 Yarrowia lipolytica
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.2.1.48 0.00879
-
glucose-grown cell Candida tropicalis
1.2.1.48 0.0932
-
stearyl alcohol-grown cell Candida tropicalis
1.2.1.48 0.098
-
alkane-grown cell Candida tropicalis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.48 long-chain aldehyde + NAD+ in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis Yarrowia lipolytica ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis Candida tropicalis ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents Yarrowia lipolytica ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents Candida tropicalis ?
-
?
1.2.1.48 long-chain aldehyde + NAD+ + H2O
-
Yarrowia lipolytica long-chain acid anion + NADH
-
?
1.2.1.48 long-chain aldehyde + NAD+ + H2O
-
Candida tropicalis long-chain acid anion + NADH
-
?

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.48 NAD+
-
Yarrowia lipolytica
1.2.1.48 NAD+
-
Candida tropicalis