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Literature summary extracted from

  • Parli, C.J.; Krieter, P.; Schmidt, B.
    Metabolism of 6-chlorotryptophan to 4-chloro-3-hydroxyanthranilic acid: a potent inhibitor of 3-hydroxyanthranilic acid oxidase (1980), Arch. Biochem. Biophys., 203, 161-166.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.10.3.5 4-Chloro-3-hydroxyanthranilate irreversible inhibition Cavia porcellus
1.10.3.5 4-Chloro-3-hydroxyanthranilate irreversible inhibition Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.5 Cavia porcellus
-
 guinea pig
-
1.10.3.5 Rattus norvegicus
-
 Wistar
-
1.10.3.5 Rattus norvegicus Wistar
-
 Wistar
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.10.3.5 kidney
-
 Cavia porcellus
-
1.10.3.5 kidney
-
 Rattus norvegicus
-
1.10.3.5 liver
-
 Cavia porcellus
-
1.10.3.5 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.5 2 3-hydroxyanthranilic acid + 2 O2
-
 Cavia porcellus 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
1.10.3.5 2 3-hydroxyanthranilic acid + 2 O2
-
 Rattus norvegicus 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
1.10.3.5 2 3-hydroxyanthranilic acid + 2 O2
-
 Rattus norvegicus Wistar 2-amino-2H-phenoxazin-3-one-1,9-dicarboxylic acid + 2 H2O2
-
 ?
1.10.3.5 3-hydroxy-L-kynurenine + O2
-
 Rattus norvegicus (2S)-2-amino-4-(6-imino-5-oxocyclohexa-1,3-dien-1yl)-4-oxo-butanoic acid + H2O2
-
 ?
1.10.3.5 3-hydroxy-L-kynurenine + O2
-
 Rattus norvegicus Wistar (2S)-2-amino-4-(6-imino-5-oxocyclohexa-1,3-dien-1yl)-4-oxo-butanoic acid + H2O2
-
 ?