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Literature summary extracted from

  • Bright, H.J.; Porter, D.J.T.
    Flavoprotein oxidases (1975), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 12, 421-505.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.3.4 Br- competitive, at low pH Aspergillus niger
1.1.3.4 Br- competitive, at low pH Penicillium amagasakiense
1.1.3.4 Cl- competitive, at low pH Aspergillus niger
1.1.3.4 Cl- competitive, at low pH Penicillium amagasakiense
1.1.3.4 F- competitive, at low pH Aspergillus niger
1.1.3.4 F- competitive, at low pH Penicillium amagasakiense

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.1.3.4 160000
-
-
Aspergillus niger
1.1.3.4 160000
-
-
Penicillium amagasakiense
1.1.3.4 186000
-
-
Aspergillus niger

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.3.4 beta-D-glucose + O2 + H2O Aspergillus niger
-
D-glucono-1,5-lactone + H2O2
-
?
1.1.3.4 beta-D-glucose + O2 + H2O Penicillium amagasakiense
-
D-glucono-1,5-lactone + H2O2
-
?

Organism

EC Number Organism UniProt Comment Textmining
1.1.3.4 Aspergillus niger
-
-
-
1.1.3.4 Penicillium amagasakiense
-
-
-
1.4.3.2 Agkistrodon piscivorus piscivorus
-
-
-
1.4.3.2 Crotalus adamanteus
-
-
-
1.4.3.3 Sus scrofa
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
1.4.3.2 an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 mechanism Crotalus adamanteus
1.4.3.2 an L-amino acid + H2O + O2 = a 2-oxo carboxylate + NH3 + H2O2 mechanism Agkistrodon piscivorus piscivorus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.3.4 beta-D-glucose + O2 + H2O
-
Aspergillus niger D-glucono-1,5-lactone + H2O2
-
?
1.1.3.4 beta-D-glucose + O2 + H2O
-
Penicillium amagasakiense D-glucono-1,5-lactone + H2O2
-
?
1.1.3.4 beta-D-glucose + O2 + H2O kinetic mechanism Aspergillus niger D-glucono-1,5-lactone + H2O2
-
?
1.1.3.4 beta-D-glucose + O2 + H2O kinetic mechanism Penicillium amagasakiense D-glucono-1,5-lactone + H2O2
-
?
1.1.3.4 beta-D-glucose + O2 + H2O glucose is the primary substrate for the enzyme Aspergillus niger D-glucono-1,5-lactone + H2O2
-
?
1.4.3.2 L-amino acid + H2O + O2
-
Crotalus adamanteus 2-oxo acid + NH3 + H2O2
-
?
1.4.3.2 L-amino acid + H2O + O2
-
Agkistrodon piscivorus piscivorus 2-oxo acid + NH3 + H2O2
-
?

Subunits

EC Number Subunits Comment Organism
1.1.3.4 dimer
-
Aspergillus niger
1.1.3.4 dimer each unit in the dimer is composed of two polypeptide chains connected by a disulfide bond Penicillium amagasakiense

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.3.4 FAD defined as flavoprotein oxidase, two very tightly bound FAD molecules per dimer, kinetic behavior Aspergillus niger
1.1.3.4 FAD defined as flavoprotein oxidase, two very tightly bound FAD molecules per dimer, kinetic behavior Penicillium amagasakiense
1.4.3.2 FAD 2 mol of FAD per mol of enzyme Crotalus adamanteus
1.4.3.2 FAD 2 mol of FAD per mol of enzyme Agkistrodon piscivorus piscivorus
1.4.3.3 FAD flavoprotein Sus scrofa