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Literature summary extracted from

  • Vidal-Leiria, M.; Van Uden, N.
    Inositol dehydrogenase from the yeast Cryptococcus melibiosum (1973), Biochim. Biophys. Acta, 293, 295-303.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.18 NADH competitive inhibition with NAD+ as variable substrate, bi-bi mechanism Myxozyma melibiosi
1.1.1.18 scyllo-inosose non-competitive inhibition with myo-inositol as varied substrate, uncompetitive with NAD+ as variable substrate, bi-bi ordered mechanism Myxozyma melibiosi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.1.1.18 myo-inositol + NAD+ Myxozyma melibiosi
-
 scyllo-inosose + NADH
-
 r

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.18 Myxozyma melibiosi
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.1.1.18 partial Myxozyma melibiosi

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.1.1.18 cell culture
-
 Myxozyma melibiosi
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.1.1.18 1.68
-
-
 Myxozyma melibiosi

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.18 myo-inositol + NAD+
-
 Myxozyma melibiosi scyllo-inosose + NADH
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.18 NAD+ can not be replaced by NADP+ Myxozyma melibiosi
1.1.1.18 NADH
-
 Myxozyma melibiosi