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Literature summary extracted from
- Purification and kinetic properties of chalcone-flavanone isomerase from soya bean (1975), Eur. J. Biochem., 50, 383-389.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 5.5.1.6 | 5,7,3',4',5'-Pentahydroxyflavonol | i.e. myricetin, inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max |  |
| 5.5.1.6 | 5,7,4'-Trihydroxyflavanone | i.e. naringenin, inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 5,7,4'-trihydroxyflavone | i.e. apigenin, inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 5,7,4'-trihydroxyflavonol | i.e. kaempferol, inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 6,4'-Dihydroxyaurone | inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 7,3',4'-Trihydroxyflavonol | i.e. fisetin, inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 7,3'-Dihydroxy-4'-methoxyflavonol | inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 7,4'-Dihydroxyflavone | inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 7,4'-dihydroxyflavonol | inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
| 5.5.1.6 | 7-Hydroxy,4'-methoxyflavone | inhibits isomerization of 4,2',4'-trihydroxychalcone | Glycine max | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.5.1.6 | 0.004 | - |
liquiritigenin | - |
Glycine max | |
| 5.5.1.6 | 0.018 | - |
4,2',4'-trihydroxychalcone | - |
Glycine max | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.6 | 15600 | - |
meniscus-depletion equilibrium sedimentation | Glycine max |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.5.1.6 | additional information | Glycine max | the enzyme plays an important role in flavonoid metabolism | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 5.5.1.6 | Glycine max | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 5.5.1.6 | - |
Glycine max |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 5.5.1.6 | seed | - |
Glycine max | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.6 | additional information | - |
- |
Glycine max |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 5.5.1.6 | 4,2',4',6'-Tetrahydroxychalcone | - |
Glycine max | 5,7,4'-Trihydroxyflavanone | i.e. naringenin | ? | |
| 5.5.1.6 | 4,2',4'-trihydroxychalcone | r, at pH 7.6 | Glycine max | (2S)-4',7-dihydroxyflavanone | the product is liquiritigenin | ? | |
| 5.5.1.6 | additional information | the enzyme plays an important role in flavonoid metabolism | Glycine max | ? | - |
? | |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 5.5.1.6 | additional information | - |
additional information | - |
Glycine max |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 5.5.1.6 | 7 | 8.7 | isomerization of 4,2',4'-trihydroxychalcone | Glycine max |
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